Evidence map›Paper›PMID 22143898›Full record

ReviewMycopathologia2012

Induction of protective immunity against cryptococcosis.

Karen L Wozniak, Sarah Hardison, Michal Olszewski, Floyd L Wormley

Open access · hybridAbstract readReview
PubMed Publisher
In one paragraph

Review in Mycopathologia, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 20 citations in OpenAlex.

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  4. Lack of an atypical PDR transporter generates an immunogenicbioRxiv : the preprint server for biology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Karen L WozniakDepartment of Biology, The University of Texas, San Antonio, TX 78249-0062, USA.
Sarah Hardison
Michal Olszewski
Floyd L Wormley
The University of Texas at San Antonio · USTexas Center for Infectious Disease · USVA Ann Arbor Healthcare System · US

Funding

Protective Host Immunity Against Pulmonary CryptococcosisR01AI071752 · NIAID · UNIVERSITY OF TEXAS SAN ANTONIO · PI WORMLEY, FLOYD L. · 2007 to 2018
$3.7M
Identification of C. neoformans proteins that induce protective immunity.R21AI083718 · NIAID · UNIVERSITY OF TEXAS SAN ANTONIO · PI WORMLEY, FLOYD L. · 2010 to 2011
$396k
NIAID NIH HHS R01AI071752-05NIAID NIH HHS R21 AI083718-02
6 · The paper itself

Abstract

Cryptococcus neoformans, the predominant etiological agent of cryptococcosis, is an encapsulated fungal pathogen that can cause life-threatening infections of the central nervous system in immune compromised individuals resulting in high morbidity and mortality. Consequently, several studies have endeavored to understand those mechanisms that mediate resistance and susceptibility to Cryptococcus infection. In this review, we will examine the contributions of various components of the innate and adaptive immune response toward protection against cryptococcosis. We will focus our discussion on studies presented at the 8th International Conference on Cryptococcus and Cryptococcosis (ICCC). Remarkable progress has been made toward our understanding of host immunity and susceptibility to cryptococcal infection and the potential for vaccine development.

Indexed as

Host-Pathogen InteractionsAnimalsCongresses as TopicCryptococcosisCryptococcus neoformansHumans

Identifiers

PMID22143898
OpenAlexW1975410981

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.