Evidence map›Paper›PMID 22143879›Full record

ReviewMolecular biology reports2012

NutriTRAILomics in prostate cancer: time to have two strings to one's bow.

Ammad Ahmad Farooqi, Aamir Rana, Asma M Riaz, Ammara Khan, Muhammad Ali, Sara Javed, Shahzeray Mukhtar, Sehrish Minhaj, Javeria Rafique Rao, Javairia Rajpoot and 5 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Ammad Ahmad FarooqiInstitute of Molecular Biology and Biotechnology (IMBB), The University of Lahore, Lahore, Pakistan. ammadahmad638@yahoo.com
Aamir Rana
Asma M Riaz
Ammara Khan
Muhammad Ali
Sara Javed
Shahzeray Mukhtar
Sehrish Minhaj
Javeria Rafique Rao
Javairia Rajpoot
Rafia Amber
Fiza Asif Javed
Waqar-Un-Nisa
Reema Khanum
Shahzad Bhatti
University of Lahore · PKNational University of Sciences and Technology · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The astonishing development of broad genomics and proteomics tools have catalyzed a new era in both therapeutic interventions and nutrition in prostate cancer. The terms pharmacogenomics and nutrigenomics have been derived out of their genetic forbears as large-scale genomics technologies have been established in the last decade. It is unquestionable that rationale of both disciplines is to individualize or personalize medicine and food and nutrition, and eventually health, by tailoring the drug or the food to the individual genotype. The purpose of this review is to significantly inspect results from current research concerning the mechanisms of action of phytonutrients and potential effects on prostate cancer. Substantial emerging data supports the synergistic adiministration of nutraceuticals with TRAIL in prostate cancer progression to circumvent TRAIL refractoriness. Nonetheless, developing novel scientific methods for discovery, validation, characterization and standardization of these multicomponent phyto-therapeutics is vital to their recognition into mainstream medicine. The key to interpret a personalized response is a greater comprehension of nutrigenomics, proteomics and metabolomics.

Indexed as

Dietary SupplementsNutrigenomicsHumansMaleModels, BiologicalProstatic NeoplasmsTNF-Related Apoptosis-Inducing LigandTNF-Related Apoptosis-Inducing Ligand

Identifiers

PMID22143879
OpenAlexW2009235834

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.