ArticleEuropean journal of applied physiology2012
Effects of cuff width on arterial occlusion: implications for blood flow restricted exercise.
Article in European journal of applied physiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 165 papers, 8 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
165 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Effects of combined blood flow restriction and neuromuscular electrical stimulation on skeletal muscle hypertrophy in adults: a systematic review and meta analysis.Scientific reports · 2026Pooled it
- Comparing adaptations from blood flow restriction exercise training using regulated or unregulated pressure systems: A systematic review and meta-analysis.Clinical rehabilitation · 2024Pooled it
- Blood flow restriction combined with resistance training on muscle strength and thickness improvement in young adults: a systematic review, meta-analysis, and meta-regression.Frontiers in physiology · 2024Pooled it
- The effects of lower limb ischaemic preconditioning: a systematic review.Frontiers in physiology · 2023Pooled it
- Is There a Minimum Effective Dose for Vascular Occlusion During Blood Flow Restriction Training?Frontiers in physiology · 2022Pooled it
- Effects of blood flow restriction without additional exercise on strength reductions and muscular atrophy following immobilization: A systematic review.Journal of sport and health science · 2020Pooled it
- Magnitude of Muscle Strength and Mass Adaptations Between High-Load Resistance Training Versus Low-Load Resistance Training Associated with Blood-Flow Restriction: A Systematic Review and Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2018Pooled it
- The addition of blood flow restriction to resistance exercise in individuals with knee pain: a systematic review and meta-analysis.Brazilian journal of physical therapyPooled it
- The Acute Effects of Blood Flow Restriction on Ankle Muscle Reaction Time and Proprioception in Healthy Individuals.Journal of sports science & medicine · 2026Trial
- Rehabilitation efficacy of Low-Load blood flow restriction training for lateral patellar compression syndrome.Journal of orthopaedic surgery and research · 2026Trial
- Trial
- Effects of a low-load multi-component training program with blood flow restriction versus the same program without blood flow restriction on muscle thickness and functional outcomes in physically inactive young adults: randomized controlled trial.Frontiers in physiology · 2026Trial
- Effects of blood flow restricted staircase sprint snacks on body composition, anaerobic power, and muscle strength in physically inactive students.Scientific reports · 2025Trial
- Effects of Blood Flow Restriction Resistance Exercise Versus Traditional Resistance Exercise in Voluntary Exhaustion on Quadriceps Muscle Adaptations in Untrained Young Males: A Randomized Trial.Medicina (Kaunas, Lithuania) · 2025Trial
- Short-duration ischemic preconditioning does not improve jump or change of direction performance in elite male handball players.PloS one · 2025Trial
- Trial
- Acute physiological responses of blood flow restriction between high-intensity interval repetitions in trained cyclists.European journal of sport science · 2024Trial
- Continuous blood flow restriction during repeated-sprint exercise increases peripheral but not systemic physiological and perceptual demands.European journal of sport science · 2024Trial
- Low-load Resistance Exercise with Perceptually Primed Practical Blood Flow Restriction Induces Similar Motor Performance Fatigue, Physiological Changes, and Perceptual Responses Compared to Traditional Blood Flow Restriction in Males and Females.Journal of sports science & medicine · 2024Trial
- Acute Response of Sclerostin to Whole-body Vibration with Blood Flow Restriction.International journal of sports medicine · 2021Trial
105 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
The purpose of this study was to determine the difference in cuff pressure which occludes arterial blood flow for two different types of cuffs which are commonly used in blood flow restriction (BFR) research. Another purpose of the study was to determine what factors (i.e., leg size, blood pressure, and limb composition) should be accounted for when prescribing the restriction cuff pressure for this technique. One hundred and sixteen (53 males, 63 females) subjects visited the laboratory for one session of testing. Mid-thigh muscle (mCSA) and fat (fCSA) cross-sectional area of the right thigh were assessed using peripheral quantitative computed tomography. Following the mid-thigh scan, measurements of leg circumference, ankle brachial index, and brachial blood pressure were obtained. Finally, in a randomized order, arterial occlusion pressure was determined using both narrow and wide restriction cuffs applied to the most proximal portion of each leg. Significant differences were observed between cuff type and arterial occlusion (narrow: 235 (42) mmHg vs. wide: 144 (17) mmHg; p = 0.001, Cohen's D = 2.52). Thigh circumference or mCSA/fCSA with ankle blood pressure, and diastolic blood pressure, explained the most variance in the cuff pressure required to occlude arterial flow. Wide BFR cuffs restrict arterial blood flow at a lower pressure than narrow BFR cuffs, suggesting that future studies account for the width of the cuff used. In addition, we have outlined models which indicate that restrictive cuff pressures should be largely based on thigh circumference and not on pressures previously used in the literature.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.