ArticleAIDS and behavior2012
OPRM1 and diagnosis-related posttraumatic stress disorder in binge-drinking patients living with HIV.
Article in AIDS and behavior, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02611362 (A Multilevel Gaming Intervention for Persons on PrEP), which is not on this map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Multilevel Gaming Intervention for Persons on PrEP
Who cites it
14 citing papers in PubMed, 21 citations in OpenAlex.
- The impact of childhood maltreatment and parental styles on telomere length: the modulatory role of A118G.European journal of psychotraumatology · 2025Article
- A novel theory on the predictive value of variation in the β-endorphin system on the risk and severity of PTSD.Military psychology : the official journal of the Division of Military Psychology, American Psychological Association · 2020Review
- A cluster-analytic approach to determining drinking motives and personality typologies: Trauma group differences and respective relations to PTSD and problematic alcohol use.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2018Article
- Neural and psychological characteristics of college students with alcoholic parents differ depending on current alcohol use.Progress in neuro-psychopharmacology & biological psychiatry · 2018Article
- Evidence of Shared Genome-Wide Additive Genetic Effects on Interpersonal Trauma Exposure and Generalized Vulnerability to Drug Dependence in a Population of Substance Users.Journal of traumatic stress · 2016Article
- Coping Expectancies, Not Enhancement Expectancies, Mediate Trauma Experience Effects on Problem Alcohol Use: A Prospective Study From Early Childhood to Adolescence.Journal of studies on alcohol and drugs · 2015Article
- An Overview of Translationally Informed Treatments for Posttraumatic Stress Disorder: Animal Models of Pavlovian Fear Conditioning to Human Clinical Trials.Biological psychiatry · 2015Review
- Mouse model of OPRM1 (A118G) polymorphism increases sociability and dominance and confers resilience to social defeat.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Drinking motives among HIV primary care patients.AIDS and behavior · 2014Article
- Effect of OPRM1 and stressful life events on symptoms of major depression in African American adolescents.Journal of affective disorders · 2014Article
- Drinking motives moderate daily relationships between PTSD symptoms and alcohol use.Journal of abnormal psychology · 2014Article
- Pharmacological secondary prevention of PTSD in youth: challenges and opportunities for advancement.Journal of traumatic stress · 2012Review
- Diagnosis and Healing In Veterans Suspected of Suffering from Post-Traumatic Stress Disorder (PTSD) Using Reward Gene Testing and Reward Circuitry Natural Dopaminergic Activation.Journal of genetic syndromes & gene therapy · 2012Article
- Temperament traits, social support, and trauma symptoms among HIV/AIDS and chronic pain patients.International journal of clinical and health psychology : IJCHPArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 5 institutions in 1 country.
Funding
Abstract
Posttraumatic stress disorder (PTSD) has been linked to numerous negative outcomes in persons living with HIV (PLH) and there is evidence that PTSD symptoms may play a role in maintaining alcohol use problems. The opioid receptor mu-1 (OPRM1) gene may play a role in both PTSD and alcohol use. We examined the association between PTSD and drinking motives as well as variation in the OPRM1 as a predictor of both PTSD and drinking motives in a sample of 201 PLH reporting recent binge drinking. Self-reported PTSD symptom severity was significantly associated with drinking motives for coping, enhancement, and socialization. OPRM1 variation was associated with decreased PTSD symptom severity as well as enhancement motives for drinking.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.