Evidence map›Paper›PMID 22143526›Full record

ArticleAntimicrobial agents and chemotherapy2012

Tn125-related acquisition of blaNDM-like genes in Acinetobacter baumannii.

Laurent Poirel, Rémy A Bonnin, Anne Boulanger, Jacques Schrenzel, Martin Kaase, Patrice Nordmann

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 129 papers.

0numbers the graph read from it
0cells of the map it votes in
129citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

129 citing papers in PubMed, 208 citations in OpenAlex.

  1. Article
  2. Convergent evolution of ST2 and ST164 mediates dissemination of the blaAnnals of clinical microbiology and antimicrobials · 2026
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  3. Article
  4. Genetic and Phenotypic Characterization of aAntibiotics (Basel, Switzerland) · 2026
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  5. Genomic Epidemiology of NDM-1 Carbapenemase-ProducingAntibiotics (Basel, Switzerland) · 2026
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  6. Genetic Characterization of Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2026
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  7. Article
  8. Article
  9. Article
  10. Deciphering the genomic landscape of novelFrontiers in microbiology · 2026
    Article
  11. Dissemination of aFrontiers in microbiology · 2026
    Article
  12. Article
  13. Article
  14. Article
  15. Genetic features of blaBMC microbiology · 2025
    Article
  16. Article
  17. Article
  18. Genomic Characterization of a Carbapenem-ResistantPathogens (Basel, Switzerland) · 2025
    Article
  19. Plasmid genomic epidemiology ofMicrobial genomics · 2025
    Article
  20. NDM- or VIM-producing Citrobacter spp. in Poland, 2011-19: high genetic diversity with broader representation of ST8, ST18 and ST22 global clones.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article

69 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 4 countries.

Laurent PoirelService de Bactériologie-Virologie, INSERM U914, Emerging Resistance to Antibiotics, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine et Université Paris-Sud, K.-Bicêtre, France.
Rémy A Bonnin
Anne Boulanger
Jacques Schrenzel
Martin Kaase
Patrice Nordmann
Assistance Publique – Hôpitaux de Paris · FRBicêtre Hospital · FRGeneva College · USInserm · FRRuhr University Bochum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A multidrug-resistant Acinetobacter baumannii isolate recovered from a patient hospitalized in Switzerland after a transfer from Serbia produced the NDM-1 carbapenemase. The bla(NDM-1) gene was part of a chromosomally located Tn125 composite transposon bracketed by two copies of the same insertion sequence, ISAba125. This transposon was also associated with the acquisition and expression of the bla(NDM-2) gene in an A. baumannii isolate in Germany. Tn125 appears to be the main vehicle for dissemination of bla(NDM) genes in that species.

Indexed as

Acinetobacter baumanniiAcinetobacter InfectionsAnti-Bacterial AgentsBacterial Proteinsbeta-Lactamasesbeta-Lactam Resistancebeta-LactamsCarbapenemsDNA Transposable ElementsDrug Resistance, Multiple, BacterialGene Transfer, HorizontalHumansMicrobial Sensitivity TestsMolecular Sequence DataSequence Analysis, DNASwitzerlandAnti-Bacterial AgentsBacterial Proteinsbeta-lactamase NDM-1beta-Lactamasesbeta-LactamscarbapenemaseCarbapenemsDNA Transposable Elements

Identifiers

PMID22143526
PMCPMC3264265
OpenAlexW2014477899

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.