ReviewNature reviews. Clinical oncology2011
Neurosurgical management of metastases in the central nervous system.
Review in Nature reviews. Clinical oncology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 42 citations in OpenAlex.
- Prognostic factors and outcome of surgically treated patients with brain metastases of non-small cell lung cancer.Thoracic cancer · 2019Trial
- Trial
- Spinal cord Compression Outcomes Of Treatment (SCOOT) Delphi study.Journal of spine surgery (Hong Kong) · 2026Review
- Editorial: It takes a village: The expanding multi-disciplinary approach to brain metastasis.Frontiers in oncology · 2022Article
- Prognostic Factors and Survival Benefits of Antitumor Treatments for Advanced Non-Small Cell Lung Cancer Patients With Central Nervous System Metastasis With or Without Driver Genes: A Chinese Single-Center Cohort Study.Frontiers in oncology · 2022Article
- Inpatient palliative care utilization for patients with brain metastases.Neuro-oncology practice · 2021Article
- Perioperative mortality of metastatic spinal disease with unknown primary: A case report and review of literature.World journal of clinical cases · 2021Article
- Full-field swept-source optical coherence tomography and neural tissue classification for deep brain imaging.Journal of biophotonics · 2020Article
- Operative and peri-operative considerations in the management of brain metastasis.Cancer medicine · 2019Review
- Prospective memory impairment following whole brain radiotherapy in patients with metastatic brain cancer.Cancer medicine · 2018Article
- Single fraction spine stereotactic ablative body radiotherapy with volumetric modulated arc therapy.Journal of neuro-oncology · 2017Article
- Pre-treatment factors associated with detecting additional brain metastases at stereotactic radiosurgery.Journal of neuro-oncology · 2016Article
- Factors Associated with Life Expectancy in Patients with Metastatic Spine Disease from Adenocarcinoma of the Lung.Global spine journal · 2015Article
- Survival and recurrence for patients undergoing surgery of skull base intracranial metastases.Journal of neurological surgery. Part B, Skull base · 2013Article
- Identifying better surgical candidates among recursive partitioning analysis class 2 patients who underwent surgery for intracranial metastases.World neurosurgeryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metastases in the central nervous system (CNS) are identified in up to 30% of patients at autopsy. Rates of CNS involvement in metastatic cancer are believed to be increasing, possibly owing to better control of systemic disease with novel chemotherapies or improved metastasis detection. The neurosurgical treatment of patients with metastatic cancer is an integral component of multimodality therapy for brain and spinal metastases. Survival benefit has been demonstrated for the addition of open surgery as well as the use of stereotactic radiosurgery (SRS) to whole-brain radiation therapy for treatment of patients with isolated cranial and spinal metastases compared with whole-brain radiation therapy alone. New clinical trials that directly compare open surgical procedures with SRS are underway, as are trials examining the role of neurosurgical procedures, such as vertebroplasty and kyphoplasty, in association with radiotherapy as methods for pain control in cancer patients with metastatic lesions in the spinal column. In this article, I review data from current randomized clinical trials that examine the role of neurosurgical intervention in the treatment of patients with CNS metastases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.