ArticlePain management2011
The brain in chronic pain: clinical implications.
Article in Pain management, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Altered brain function and structure in carpal tunnel syndrome: a systematic review and meta-analysis of structural and functional brain imaging.Brain structure & function · 2024Pooled it
- Brain Responses to Noxious Stimuli in Patients With Chronic Pain: A Systematic Review and Meta-analysis.JAMA network open · 2021Pooled it
- Optimizing Chronic Pain Treatment with Enhanced Neuroplastic Responsiveness: A Pilot Randomized Controlled Trial.Nutrients · 2021Trial
- Unlearning chronic pain: A randomized controlled trial to investigate changes in intrinsic brain connectivity following Cognitive Behavioral Therapy.NeuroImage. Clinical · 2014Trial
- More than chronic pain: behavioural and psychosocial protective factors predict lower brain age in adults with/at risk of knee osteoarthritis over two years.Brain communications · 2025Article
- Article
- Environmental and sociocultural factors are associated with pain-related brain structure among diverse individuals with chronic musculoskeletal pain: intersectional considerations.Scientific reports · 2024Article
- Reduced somatosensory evoked potentials and paired-pulse inhibition in the primary somatosensory cortex of athletes with chronic pain.European journal of applied physiology · 2023Article
- The waiting game: investigating the neurobiological transition from acute to persistent pain in adolescent rats.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Lifeworlds in pain: a principled method for investigation and intervention.Neuroscience of consciousness · 2023Review
- Rating Dyspnea and Pain: "No" is Not Always "Zero".Clinical nursing research · 2023Article
- Chronic Pain Severity and Sociodemographics: An Evaluation of the Neurobiological Interface.The journal of pain · 2022Observational
- Objective evidence for chronic back pain relief by Medical Yoga therapy.Frontiers in pain research (Lausanne, Switzerland) · 2022Article
- Association between Self-Reported Pain, Cognition, and Neuropathology in Older Adults Admitted to an Outpatient Memory Clinic-A Cross-Sectional Study.Brain sciences · 2021Article
- Plastic Changes in Pain and Motor Network Induced by Chronic Burn Pain.Journal of clinical medicine · 2021Article
- Resilience, pain, and the brain: Relationships differ by sociodemographics.Journal of neuroscience research · 2021Observational
- Aberrant plasticity in musculoskeletal pain: a failure of homeostatic control?Experimental brain research · 2021Article
- Functional Disruptions of the Brain in Low Back Pain: A Potential Imaging Biomarker of Functional Disability.Frontiers in neurology · 2021Article
- Enhanced amygdala-frontal operculum functional connectivity during rest in women with chronic neck pain: Associations with impaired conditioned pain modulation.NeuroImage. Clinical · 2021Article
- Withdrawal-associated injury site pain prevalence and correlates among opioid-using people who inject drugs in Vancouver, Canada.Drug and alcohol dependence · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
This article examines the present, and potential future, impact of brain imaging on chronic pain. It is argued that novel theories of chronic pain are coming to the fore, specifically through brain imaging of the human brain in chronic pain. Such studies show that the brain reorganizes in relation to chronic pain, in a pattern specific to the type of clinical pain, and that brain networks and receptor targets are being identified and reverse translated to animal studies of their efficacy and mechanisms. Future studies need to integrate across human brain imaging techniques, as well as more intensive reverse translational methods.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.