Evidence map›Paper›PMID 22140108›Full record

ArticleNucleic acids research2012

CharProtDB: a database of experimentally characterized protein annotations.

Ramana Madupu, Alexander Richter, Robert J Dodson, Lauren Brinkac, Derek Harkins, Scott Durkin, Susmita Shrivastava, Granger Sutton, Daniel Haft

Abstract read
In one paragraph

Article in Nucleic acids research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Interactive tools for functional annotation of bacterial genomes.Database : the journal of biological databases and curation · 2024
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  9. TIGRFAMs and Genome Properties in 2013.Nucleic acids research · 2013
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ramana MadupuJ Craig Venter institute, 9704 Medical Center Drive Rockville, MD 20850, USA. rmadupu@jcvi.org
Alexander Richter
Robert J Dodson
Lauren Brinkac
Derek Harkins
Scott Durkin
Susmita Shrivastava
Granger Sutton
Daniel Haft

Funding

Algorithmically-Tuned Protein Families, Rule_Base and Characterized ProteinsR01HG004881 · NHGRI · J. CRAIG VENTER INSTITUTE, INC. · PI HAFT, DANIEL H. · 2008 to 2010
$1.6M
NHGRI NIH HHS R01 HG004881
6 · The paper itself

Abstract

CharProtDB (http://www.jcvi.org/charprotdb/) is a curated database of biochemically characterized proteins. It provides a source of direct rather than transitive assignments of function, designed to support automated annotation pipelines. The initial data set in CharProtDB was collected through manual literature curation over the years by analysts at the J. Craig Venter Institute (JCVI) [formerly The Institute of Genomic Research (TIGR)] as part of their prokaryotic genome sequencing projects. The CharProtDB has been expanded by import of selected records from publicly available protein collections whose biocuration indicated direct rather than homology-based assignment of function. Annotations in CharProtDB include gene name, symbol and various controlled vocabulary terms, including Gene Ontology terms, Enzyme Commission number and TransportDB accession. Each annotation is referenced with the source; ideally a journal reference, or, if imported and lacking one, the original database source.

Indexed as

Databases, ProteinMolecular Sequence AnnotationProteinsProteins

Identifiers

PMID22140108
PMCPMC3245046

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.