Evidence map›Paper›PMID 22140063›Full record

ReviewLiver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society2012

Cell therapies for liver diseases.

Yue Yu, James E Fisher, Joseph B Lillegard, Brian Rodysill, Bruce Amiot, Scott L Nyberg

Open access · bronzeAbstract readReview
In one paragraph

Review in Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 100 citations in OpenAlex.

  1. Frontiers in bioengineering and biotechnology · 2025
    Article
  2. Article
  3. Review
  4. Article
  5. Customizable Microfluidic Origami Liver-on-a-Chip (oLOC).Advanced materials technologies · 2022
    Article
  6. Review
  7. Article
  8. Article
  9. Experimental and therapeutic medicine · 2020
    Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Regenerative Medicine and the Biliary Tree.Seminars in liver disease · 2017
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Yue YuDivision of Experimental Surgery, Department of Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
James E Fisher
Joseph B Lillegard
Brian Rodysill
Bruce Amiot
Scott L Nyberg
Mayo Clinic in Arizona · USNanjing Medical University · CN

Funding

XENOGENEIC BIOARTIFICAL LIVERR01DK056733 · NIDDK · MAYO CLINIC ROCHESTER · PI NYBERG, SCOTT L · 1999 to 2010
$1.4M
NIDDK NIH HHS R01 DK056733
6 · The paper itself

Abstract

Cell therapies, which include bioartificial liver support and hepatocyte transplantation, have emerged as potential treatments for a variety of liver diseases. Acute liver failure, acute-on-chronic liver failure, and inherited metabolic liver diseases are examples of liver diseases that have been successfully treated with cell therapies at centers around the world. Cell therapies also have the potential to be widely applied to other liver diseases, including noninherited liver diseases and liver cancer, and to improve the success of liver transplantation. Here we briefly summarize current concepts of cell therapy for liver diseases.

Indexed as

AnimalsCell- and Tissue-Based TherapyDisease Models, AnimalHepatocytesHumansLiver, ArtificialLiver DiseasesStem Cell TransplantationSwine

Identifiers

PMID22140063
PMCPMC3245367
OpenAlexW1994807399

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.