ArticleClinical research in cardiology : official journal of the German Cardiac Society2012
Rapid assessment of longitudinal systolic left ventricular function using speckle tracking of the mitral annulus.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Left ventricular systolic function evaluated by strain echocardiography and relationship with mortality in patients with severe sepsis or septic shock: a systematic review and meta-analysis.Critical care (London, England) · 2018Pooled it
- A TMAD-based rapid assessment model for left ventricular systolic function in patients with coronary artery disease: a multicenter prospective development and validation study.The international journal of cardiovascular imaging · 2026Article
- Assessment of longitudinal systolic function using tissue motion annular displacement in cats with hypertrophic cardiomyopathy: a prospective case-control study.Journal of feline medicine and surgery · 2025Article
- Prognostic Value of RV Function Analysis During the Interstage Period in Patients with Hypoplastic Left Heart Syndrome.Pediatric cardiology · 2024Article
- Normal reference values for mitral annular plane systolic excursion by motion-mode and speckle tracking echocardiography: a prospective, multicentre, population-based study.European heart journal. Cardiovascular Imaging · 2023Article
- Feasibility of tissue-tracking mitral annular displacement in single four-chamber view as a simple index of left ventricular longitudinal deformation.Journal of echocardiography · 2022Article
- Behavioral and cardiovascular effects of a single dose of gabapentin or melatonin in cats: a randomized, double-blind, placebo-controlled trial.Journal of feline medicine and surgery · 2022Article
- Tissue motion annular displacement to assess the left ventricular systolic function in healthy cats.Veterinary research communications · 2022Article
- Feasibility and discriminatory value of tissue motion annular displacement in sepsis-induced cardiomyopathy: a single-center retrospective observational study.Critical care (London, England) · 2022Observational
- Prognostic value of tissue-tracking mitral annular displacement by speckle-tracking echocardiography in asymptomatic aortic stenosis patients with preserved left ventricular ejection fraction.Journal of echocardiography · 2021Article
- Comparison of mitral annular displacement and global longitudinal strain imaging for predicting significant coronary atherosclerotic disease in patients of chronic stable angina pectoris.The international journal of cardiovascular imaging · 2021Article
- Left atrial appendage morphology and cardiac function in patients with sinus rhythm.Journal of echocardiography · 2020Article
- Study on factors affecting local peak strain results in automatic functional imaging of transthoracic echocardiography.Annals of translational medicine · 2018Article
- Speckle tracking echocardiography detects decreased cardiac longitudinal function in anthracycline-exposed survivors of childhood cancer.European journal of pediatrics · 2016Article
- Relationship between epicardial adipose tissue thickness and early impairment of left ventricular systolic function in patients with preserved ejection fraction.Heart and vessels · 2016Article
- Characteristics of sepsis-induced cardiac dysfunction using speckle-tracking echocardiography: a feasibility study.Anaesthesia and intensive care · 2016Article
- Improvement of risk assessment in systemic light-chain amyloidosis using human placental growth factor.Clinical research in cardiology : official journal of the German Cardiac Society · 2015Article
- Identification of Mitral Annulus Hinge Point Based on Local Context Feature and Additive SVM Classifier.Computational and mathematical methods in medicine · 2015Article
- Right ventricular function assessment using tissue Doppler imaging and speckle tracking echocardiography.Journal of ultrasonography · 2014Review
- Classification of diastolic function with phase-contrast cardiac magnetic resonance imaging: validation with echocardiography and age-related reference values.Clinical research in cardiology : official journal of the German Cardiac Society · 2014Article
Corrections and comments
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Authors and funding
10 authors.
Funding
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Abstract
backgroundEvaluation of left ventricular function (LV) is one of the most important tasks of echocardiography. Left ventricular longitudinal function has been recognized to differentiate myocardial disorders better than ejection fraction (EF) alone. But recent parameters are still dependent on image quality and time consuming.
methodsTransthoracic echocardiography, tissue Doppler imaging, strain imaging and assessment of longitudinal function with a tissue motion annular displacement (TMAD) tracking algorithm were performed in 152 patients with various cardiac pathologies and 47 healthy volunteers in a clinical routine setting.
resultsMeasures of longitudinal function such as LV peak systolic strain (SR, r² = 0.88, p < 0.001) and peak systolic strain rate (SRR, r² = 0.78, p < 0.001) correlated highly with TMAD. Tissue motion annular displacement was ultrafast and less time-consuming compared to strain imaging (8.2 ± 2.2 s, p < 0.001). Significantly more patients with reduced image quality could be analyzed compared to strain imaging (p < 0.001). The intra- and inter-observer variabilities were very low with 1.3 ± 1% and 1.7 ± 1.2%. Tissue motion annular displacement correlated well with clinical parameters (NYHA, r = -0.71, p < 0.001) as well as NT-proBNP (r = -0.73, p < 0.001) and identified patients with structural heart disease with a significantly higher sensitivity 92.1% and specificity 95.7% than did EF, SR, SRR or NT-proBNP (Cut-off:14.2%, p < 0.01). In a subgroup of patients with systemic light chain amyloidosis and preserved EF (>50%, n = 54), TMAD was significantly reduced, especially in those without any signs of cardiac involvement and was superior to other parameters of longitudinal function (p < 0.05).
conclusionsTissue motion annular displacement is a rapid, sensitive and reproducible method for the assessment of LV longitudinal function, which is less dependent on image quality.
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