ArticleNature nanotechnology2011
Label-free imaging of semiconducting and metallic carbon nanotubes in cells and mice using transient absorption microscopy.
Article in Nature nanotechnology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 107 citations in OpenAlex.
- Mechanically strong and highly conductive graphitized carbon nanowire arrays for nano-fabrication of carbon-based chips.Microsystems & nanoengineering · 2026Article
- Roadmap on Label-Free Super-Resolution Imaging.Laser & photonics reviews · 2023Article
- Carbonaceous Nanoparticle Air Pollution: Toxicity and Detection in Biological Samples.Nanomaterials (Basel, Switzerland) · 2022Review
- The use of advanced spectral imaging to reveal nanoparticle identity in biological samples.Nanoscale · 2022Article
- Transient absorption microscopy: Technological innovations and applications in materials science and life science.The Journal of chemical physics · 2020Article
- Detection and Quantification of Graphene-Family Nanomaterials in the Environment.Environmental science & technology · 2018Review
- Compressed supercontinuum probe for transient absorption microscopy.Optics letters · 2018Article
- Label-Free Imaging of Heme Dynamics in Living Organisms by Transient Absorption Microscopy.Analytical chemistry · 2018Article
- Label-free imaging of hemoglobin degradation and hemosiderin formation in brain tissues with femtosecond pump-probe microscopy.Theranostics · 2018Article
- Quantification of Carbon Nanotubes in Environmental Matrices: Current Capabilities, Case Studies, and Future Prospects.Environmental science & technology · 2016Review
- Biodegradation of Single-Walled Carbon Nanotubes in Macrophages through Respiratory Burst Modulation.International journal of molecular sciences · 2016Article
- Invited Review Article: Pump-probe microscopy.The Review of scientific instruments · 2016Review
- Scanning color optical tomography (SCOT).Optics express · 2015Article
- Highly sensitive transient absorption imaging of graphene and graphene oxide in living cells and circulating blood.Scientific reports · 2015Article
- Coherent Raman Scattering Microscopy in Biology and Medicine.Annual review of biomedical engineering · 2015Review
- Transient absorption microscopy of gold nanorods as spectrally orthogonal labels in live cells.Nanoscale · 2014Article
- Stealth nanotubes: strategies of shielding carbon nanotubes to evade opsonization and improve biodistribution.International journal of nanomedicine · 2014Review
- Localization and relative quantification of carbon nanotubes in cells with multispectral imaging flow cytometry.Journal of visualized experiments : JoVE · 2013Article
- Direct optical imaging of graphene in vitro by nonlinear femtosecond laser spectral reshaping.Nano letters · 2012Article
- Nanoimaging: Image contrast using time.Nature nanotechnology · 2011Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As interest in the potential biomedical applications of carbon nanotubes increases, there is a need for methods that can image nanotubes in live cells, tissues and animals. Although techniques such as Raman, photoacoustic and near-infrared photoluminescence imaging have been used to visualize nanotubes in biological environments, these techniques are limited because nanotubes provide only weak photoluminescence and low Raman scattering and it remains difficult to image both semiconducting and metallic nanotubes at the same time. Here, we show that transient absorption microscopy offers a label-free method to image both semiconducting and metallic single-walled carbon nanotubes in vitro and in vivo, in real time, with submicrometre resolution. By using appropriate near-infrared excitation wavelengths, we detect strong transient absorption signals with opposite phases from semiconducting and metallic nanotubes. Our method separates background signals generated by red blood cells and this allows us to follow the movement of both types of nanotubes inside cells and in the blood circulation and organs of mice without any significant damaging effects.
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