ReviewMolecular phylogenetics and evolution2012
The evolution of HIV: inferences using phylogenetics.
Review in Molecular phylogenetics and evolution, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
43 citing papers in PubMed.
- Genetic diversity and antiretroviral resistance of human immunodeficiency virus type 1 in Peruvian military personnel during one year of follow-upBiomedica : revista del Instituto Nacional de Salud · 2026Article
- Ethics of Identifying Individuals Involved in HIV Transmission Events by Phylogenetics in Molecular Surveillance.Bioethics · 2025Article
- Article
- phyBWT2: phylogeny reconstruction via eBWT positional clustering.Algorithms for molecular biology : AMB · 2023Article
- No Difference in the Prevalence of HIV-1Vaccines · 2023Article
- Article
- Consequences of HIV infection in the bone marrow niche.Frontiers in immunology · 2023Review
- The NeuroinflammatoryPotential of HIV-1 NefVariants in Modulating the Gene Expression Profile of Astrocytes.Cells · 2022Article
- Article
- The evolution of the HIV-1 protease folding stability.Virus evolution · 2022Article
- The Origin, Epidemiology, and Phylodynamics of Human Immunodeficiency Virus Type 1 CRF47_BF.Frontiers in microbiology · 2022Article
- Prevalence of integrase strand transfer inhibitor (INSTIs) resistance mutations in Henan Province, China (2018-2020).Infection · 2021Article
- HIV-1 Persistence in Children during Suppressive ART.Viruses · 2021Review
- HAPHPIPE: Haplotype Reconstruction and Phylodynamics for Deep Sequencing of Intrahost Viral Populations.Molecular biology and evolution · 2021Article
- Phylogenetic analysis of HIV-1 shows frequent cross-country transmission and local population expansions.Virus evolution · 2021Article
- Bioinformatics Research on Drug Sensitivity Prediction.Frontiers in pharmacology · 2021Review
- Characterization of HIV-1 subtypes and drug resistance mutations in Henan Province, China (2017-2019).Archives of virology · 2020Article
- Article
- A cross-sectional study to characterize local HIV-1 dynamics in Washington, DC using next-generation sequencing.Scientific reports · 2020Article
- Evaluation of A Phylogenetic Pipeline to Examine Transmission Networks in A Canadian HIV Cohort.Microorganisms · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Molecular phylogenetics has revolutionized the study of not only evolution but also disparate fields such as genomics, bioinformatics, epidemiology, ecology, microbiology, molecular biology and biochemistry. Particularly significant are its achievements in population genetics as a result of the development of coalescent theory, which have contributed to more accurate model-based parameter estimation and explicit hypothesis testing. The study of the evolution of many microorganisms, and HIV in particular, have benefited from these new methodologies. HIV is well suited for such sophisticated population analyses because of its large population sizes, short generation times, high substitution rates and relatively small genomes. All these factors make HIV an ideal and fascinating model to study molecular evolution in real time. Here we review the significant advances made in HIV evolution through the application of phylogenetic approaches. We first examine the relative roles of mutation and recombination on the molecular evolution of HIV and its adaptive response to drug therapy and tissue allocation. We then review some of the fundamental questions in HIV evolution in relation to its origin and diversification and describe some of the insights gained using phylogenies. Finally, we show how phylogenetic analysis has advanced our knowledge of HIV dynamics (i.e., phylodynamics).
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