Evidence map›Paper›PMID 22138120›Full record

ArticleEuropean journal of radiology2013

High-resolution functional MRI of the human amygdala at 7 T.

Ronald Sladky, Pia Baldinger, Georg S Kranz, Jasmin Tröstl, Anna Höflich, Rupert Lanzenberger, Ewald Moser, Christian Windischberger

Abstract read
In one paragraph

Article in European journal of radiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Common and dissociable effects of oxytocin and lorazepam on the neurocircuitry of fear.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Trial
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Article
  8. Neurodevelopmental Pathways from Temperamental Fear to Anxiety.Current topics in behavioral neurosciences · 2025
    Review
  9. Article
  10. Leveraging ultra-high field (7T) MRI in psychiatric research.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Phenotyping Superagers Using Resting-State fMRI.AJNR. American journal of neuroradiology · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ronald SladkyMR Centre of Excellence, Medical University of Vienna, Lazarettgasse 14, 1090 Vienna, Austria. ronald.sladky@meduniwien.ac.at
Pia Baldinger
Georg S Kranz
Jasmin Tröstl
Anna Höflich
Rupert Lanzenberger
Ewald Moser
Christian Windischberger

Funding

Austrian Science Fund FWF P 23021
6 · The paper itself

Abstract

Functional magnetic resonance imaging (fMRI) has become the primary non-invasive method for investigating the human brain function. With an increasing number of ultra-high field MR systems worldwide possibilities of higher spatial and temporal resolution in combination with increased sensitivity and specificity are expected to advance detailed imaging of distinct cortical brain areas and subcortical structures. One target region of particular importance to applications in psychiatry and psychology is the amygdala. However, ultra-high field magnetic resonance imaging of these ventral brain regions is a challenging endeavor that requires particular methodological considerations. Ventral brain areas are particularly prone to signal losses arising from strong magnetic field inhomogeneities along susceptibility borders. In addition, physiological artifacts from respiration and cardiac action cause considerable fluctuations in the MR signal. Here we show that, despite these challenges, fMRI data from the amygdala may be obtained with high temporal and spatial resolution combined with increased signal-to-noise ratio. Maps of neural activation during a facial emotion discrimination paradigm at 7 T are presented and clearly show the gain in percental signal change compared to 3T results, demonstrating the potential benefits of ultra-high field functional MR imaging also in ventral brain areas.

Indexed as

AdultAlgorithmsAmygdalaBrain MappingDiscrimination, PsychologicalFemaleHumansImage EnhancementImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMalePattern Recognition, VisualReproducibility of ResultsSensitivity and Specificity

Identifiers

PMID22138120
PMCPMC3629563

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.