ArticleBrain and language2012
Co-localisation of abnormal brain structure and function in specific language impairment.
Article in Brain and language, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
71 citing papers in PubMed, 3 syntheses or guidelines pooled it, 152 citations in OpenAlex.
- The neuroanatomy of developmental language disorder: a systematic review and meta-analysis.Nature human behaviour · 2024Pooled it
- Neurodevelopmental origins of self-limiting rolandic epilepsy: Systematic review of MR imaging studies.Epilepsia open · 2021Pooled it
- What Are the Peer Interaction Strengths and Difficulties in Children with Developmental Language Disorder? A Systematic Review.International journal of environmental research and public health · 2020Pooled it
- Exploring the relationship between auditory processing characteristics and cognition in preschool children with developmental language disorder based on fNIRS.Journal of neurodevelopmental disorders · 2026Article
- The Neural Cost of Language Processing: Broader Network Recruitment in Adults With Developmental Language Disorder.Neurobiology of language (Cambridge, Mass.) · 2026Article
- Predictive value of foetal superior temporal sulcus asymmetry for neonatal speech discrimination.Brain communications · 2026Article
- Subcortical correlates of developmental language disorder: more than the neostriatum.Brain communications · 2026Article
- Developmental Language Disorder as a Multidimensional Neurodevelopmental Spectrum: Implications for Diagnosis.Journal of speech, language, and hearing research : JSLHR · 2025Review
- Structural and pragmatic language skills in school-age children relate to resting state functional connectivity.Brain imaging and behavior · 2025Article
- Spectral and Temporal Auditory Processing Skills in Children with a History of Speech and Language Delay.Journal of the American Academy of Audiology · 2025Article
- An approach to measuring language-specific brain function in developmental language disorder.Acta psychologica · 2025Article
- Brain Complexity and Parametrization of Power Spectral Density in Children with Specific Language Impairment.Entropy (Basel, Switzerland) · 2025Article
- Audiovisual speech perception deficits in unaffected siblings of children with developmental language disorder.Brain and language · 2025Article
- Beta Spectral Power during Passive Listening in Preschool Children with Specific Language Impairment.Developmental neuroscience · 2025Article
- Where do neurodevelopmental conditions fit in transdiagnostic psychiatric frameworks? Incorporating a new neurodevelopmental spectrum.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2024Article
- Procedural auditory category learning is selectively disrupted in developmental language disorder.Psychonomic bulletin & review · 2024Article
- Microstructural Properties of the Cerebellar Peduncles in Children With Developmental Language Disorder.Neurobiology of language (Cambridge, Mass.) · 2024Article
- Differences in Cortical Surface Area in Developmental Language Disorder.Neurobiology of language (Cambridge, Mass.) · 2024Article
- Neural processing of rhythmic speech by children with developmental language disorder (DLD): An EEG study.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- No evidence of altered language laterality in people who stutter across different brain imaging studies of speech and language.Brain communications · 2024Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
We assessed the relationship between brain structure and function in 10 individuals with specific language impairment (SLI), compared to six unaffected siblings, and 16 unrelated control participants with typical language. Voxel-based morphometry indicated that grey matter in the SLI group, relative to controls, was increased in the left inferior frontal cortex and decreased in the right caudate nucleus and superior temporal cortex bilaterally. The unaffected siblings also showed reduced grey matter in the caudate nucleus relative to controls. In an auditory covert naming task, the SLI group showed reduced activation in the left inferior frontal cortex, right putamen, and in the superior temporal cortex bilaterally. Despite spatially coincident structural and functional abnormalities in frontal and temporal areas, the relationships between structure and function in these regions were different. These findings suggest multiple structural and functional abnormalities in SLI that are differently associated with receptive and expressive language processing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.