ReviewProgress in molecular biology and translational science2012
Acute phase proteins in animals.
Review in Progress in molecular biology and translational science, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
89 citing papers in PubMed, 2 syntheses or guidelines pooled it, 212 citations in OpenAlex.
- Inflammatory markers as prognostic markers in patients with head and neck squamous cell carcinoma treated with immune checkpoint inhibitors: a systematic review and meta-analysis.Frontiers in oncology · 2024Pooled it
- Evidence underscoring immunological and clinical pathological changes associated with Sarcoptes scabiei infection: synthesis and meta-analysis.BMC infectious diseases · 2022Pooled it
- Subacute ruminal acidosis in high-producing dairy cows: an integrated diet-microbiota-epithelium-host framework for diagnosis and nutritional management.Journal of animal science and biotechnology · 2026Review
- Disentangling Temporal and Environmental Effects on Hematological Values in Prairie Rattlesnakes (Crotalus viridis).Journal of experimental zoology. Part A, Ecological and integrative physiology · 2026Article
- Association of Milk C-Reactive Protein With Subclinical Mastitis in Dairy Buffaloes.Veterinary medicine and science · 2026Article
- Topical Anti-Inflammatory Therapies in Veterinary Medicine: Advancing Animal Health Through a One Health Approach.Animals : an open access journal from MDPI · 2026Review
- Bacterial killing assays in ecoimmunology require cross-validation by agreement statistics.Biology open · 2026Article
- Effects of Exercise Intensity and Duration on Acute-Phase Proteins in Thoroughbred Racehorses.Animals : an open access journal from MDPI · 2026Article
- The comparison of acute phase proteins in experimentally induced canine acute pancreatitis.BMC veterinary research · 2026Article
- Impact of combined unilateral mastectomy and ovariohysterectomy on acute phase response and wound healing in dogs with mammary gland tumors.BMC veterinary research · 2026Article
- How Inflamed Is the Horse in Training? Insights into Exercise-Induced Acute Phase Response in Endurance Horses.International journal of molecular sciences · 2026Review
- Evaluation of acute phase protein, cardiac marker, and antioxidant enzymes in Madura Cattle infected with foot-and-mouth disease.Open veterinary journal · 2026Article
- Investigation of serum acute-phase protein levels and hematological and biochemical parameters in dogs with generalized demodicosis.BMC veterinary research · 2026Article
- Association between PCV and degree of azotemia with serum hepcidin concentration in cats with chronic kidney disease.Journal of veterinary internal medicine · 2026Article
- Reference interval for serum amyloid a in apparently healthy donkeys measured with a donkey-specific ELISA.Frontiers in veterinary science · 2026Article
- Predictive Prognosis Value of CRP Measurement and CAR in Dogs Infected with Parvovirus.Veterinary sciences · 2025Article
- Evaluation of serum levels of CRP and TNF-α in dogs infected withOpen veterinary journal · 2025Article
- Serum Proteinogram in the Free-Living Brazilian Common Opossum (Didelphis aurita).Electrophoresis · 2025Article
- Acute phase proteins in canine and feline fetal fluids during the second half of gestation.Veterinary and animal science · 2025Article
- Acute phase proteins as potent early biomarkers for the detection ofOpen veterinary journal · 2025Article
29 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute phase proteins (APP) were first identified in the early 1900s as early reactants to infectious disease. They are now understood to be an integral part of the acute phase response (APR) which is the cornerstone of innate immunity. APP have been shown to be valuable biomarkers as increases can occur with inflammation, infection, neoplasia, stress, and trauma. All animals--from fish to mammals--have demonstrable APP, but the type of major APP differs by species. While the primary application of these proteins in a clinical setting is prognostication, studies in animals have demonstrated relevance to diagnosis and detection and monitoring for subclinical disease. APP have been well documented in laboratory, companion, and large animals. With the advent of standardized and automated assays, these biomarkers are available for use in all fields of veterinary medicine as well as basic and clinical research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.