Evidence map›Paper›PMID 22137430›Full record

ReviewProgress in molecular biology and translational science2012

Animal models of muscular dystrophy.

Rainer Ng, Glen B Banks, John K Hall, Lindsey A Muir, Julian N Ramos, Jacqueline Wicki, Guy L Odom, Patryk Konieczny, Jane Seto, Joel R Chamberlain and 1 more

Abstract readReview
In one paragraph

Review in Progress in molecular biology and translational science, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Modeling Sarcoglycanopathy inInternational journal of molecular sciences · 2023
    Article
  6. Review
  7. In Vitro Maturation of Human Pluripotent Stem Cell-Derived Myotubes.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Lifespan Analysis of DystrophicFrontiers in physiology · 2021
    Article
  15. Article
  16. Skeletal muscle in health and disease.Disease models & mechanisms · 2020
    Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rainer NgDivision of Medical Genetics, Department of Neurology, University of Washington, Seattle, Washington, USA.
Glen B Banks
John K Hall
Lindsey A Muir
Julian N Ramos
Jacqueline Wicki
Guy L Odom
Patryk Konieczny
Jane Seto
Joel R Chamberlain
Jeffrey S Chamberlain

Funding

Assembly of the Dystrophin-Glycoprotein ComplexR01AR044533 · NIAMS · UNIVERSITY OF WASHINGTON · PI CHAMBERLAIN, JEFFREY S · 1997 to 2021
$8.9M
Dystrophin Replacement in mdx miceR37AR040864 · NIAMS · UNIVERSITY OF WASHINGTON · PI CHAMBERLAIN, JEFFREY S · 2005 to 2014
$5.0M
NIAMS NIH HHS AR044533NIAMS NIH HHS R01 AR044533NIAMS NIH HHS R37 AR040864
6 · The paper itself

Abstract

The muscular dystrophies (MDs) represent a diverse collection of inherited human disorders, which affect to varying degrees skeletal, cardiac, and sometimes smooth muscle (Emery, 2002). To date, more than 50 different genes have been implicated as causing one or more types of MD (Bansal et al., 2003). In many cases, invaluable insights into disease mechanisms, structure and function of gene products, and approaches for therapeutic interventions have benefited from the study of animal models of the different MDs (Arnett et al., 2009). The large number of genes that are associated with MD and the tremendous number of animal models that have been developed preclude a complete discussion of each in the context of this review. However, we summarize here a number of the more commonly used models together with a mixture of different types of gene and MD, which serves to give a general overview of the value of animal models of MD for research and therapeutic development.

Indexed as

Disease Models, AnimalAnimalsCalciumHumansMuscle ProteinsMuscular DystrophiesCalciumMuscle Proteins

Identifiers

PMID22137430
PMCPMC4872622

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.