Evidence map›Paper›PMID 22136388›Full record

ArticleBMC family practice2011

Guidelines on acute gastroenteritis in children: a critical appraisal of their quality and applicability in primary care.

José van den Berg, Marjolein Y Berger

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in BMC family practice, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03021109 nacompletednot on this mapstarted 2016, after this paper: background citation

Assessment of Volume Status by Measurement of Caval Index by Bedside Ultrasound in Children With Acute Gastroenteritis

TypeinterventionalSponsorDerince Training and Research HospitalRan2016 to 2017Enrolled190ConditionsDehydration, Acute GastroenteritisArmsMeasurement of inferior vena cava diameters with ultrasound
NCT03988257 phase4completednot on this mapstarted 2019, after this paper: background citation

The Effectiveness of Pleuran in Treatment of Acute Gastroenteritis in Children- a Randomized, Placebo-controlled, Double-blind Trial

TypeinterventionalSponsorMedical University of WarsawRan2019 to 2022Enrolled27ConditionsDiarrhoea, AcuteArmsImunoglukan PH4, Placebo (vitamin C syrup)
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Cost-effectiveness of oral ondansetron for children with acute gastroenteritis in primary care: a randomised controlled trial.The British journal of general practice : the journal of the Royal College of General Practitioners · 2021
    Trial
  4. Oral ondansetron for paediatric gastroenteritis in primary care: a randomised controlled trial.The British journal of general practice : the journal of the Royal College of General Practitioners · 2021
    Trial
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Acute Infectious Gastroenteritis in Infancy and Childhood.Deutsches Arzteblatt international · 2020
    Review
  14. Performance of Stool-testing Recommendations for Acute Gastroenteritis When Used to Identify Children With 9 Potential Bacterial Enteropathogens.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019
    Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

José van den BergDepartment of General Practice, Erasmus Medical Center, Erasmus University, Rotterdam, The Netherlands.
Marjolein Y Berger
Erasmus University Rotterdam · NLUniversity of Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundReasons for poor guideline adherence in acute gastroenteritis (AGE) in children in high-income countries are unclear, but may be due to inconsistency between guideline recommendations, lack of evidence, and lack of generalizability of the recommendations to general practice. The aim of this study was to assess the quality of international guidelines on AGE in children and investigate the generalizability of the recommendations to general practice.

methodsGuidelines were retrieved from websites of professional medical organisations and websites of institutes involved in guideline development. In addition, a systematic search of the literature was performed. Articles were selected if they were a guideline, consensus statement or care protocol.

resultsEight guidelines met the inclusion criteria, the quality of the guidelines varied. 242 recommendations on diagnosis and management were found, of which 138 (57%) were based on evidence.There is a large variety in the classification of symptoms to different categories of dehydration. No signs are generalizable to general practice.It is consistently recommended to use hypo-osmolar ORS, however, the recommendations on ORS-dosage are not evidence based and are inconsistent. One of 14 evidence based recommendations on therapy of AGE is based on outpatient research and is therefore generalizable to general practice.

conclusionsThe present study shows considerable variation in the quality of guidelines on AGE in children, as well as inconsistencies between the recommendations. It remains unclear how to asses the extent of dehydration and determine the preferred treatment or referral of a young child with AGE presenting in general practice.

Indexed as

GastroenteritisGuideline AdherenceOutcome and Process Assessment, Health CarePrimary Health CareAcute DiseaseChildDehydrationEvidence-Based PracticeFemaleFluid TherapyHumansMalePatient AdmissionPractice Guidelines as TopicReferral and Consultation

Identifiers

PMID22136388
PMCPMC3331832
OpenAlexW2145181431

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.