ReviewRadiation oncology (London, England)2011
Radiation techniques for acromegaly.
Review in Radiation oncology (London, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 60 citations in OpenAlex.
- Assessment of multimodal treatment options in recurrent and persistent acromegaly: a systematic review and meta-analysis.Journal of neuro-oncology · 2024Pooled it
- DEGRO practical guideline for central nervous system radiation necrosis part 1: classification and a multistep approach for diagnosis.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2022Guideline
- Endocrine and visual function after fractionated stereotactic radiotherapy of perioptic tumors.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2013Trial
- Tumor control and motor function in patients with metastases located in the primary motor cortex after stereotactic radiosurgery.Journal of neuro-oncology · 2025Article
- Article
- Radiotherapeutic advances in the management of glioblastoma.Journal of neuro-oncology · 2024Review
- Comparison of patient setup accuracy for optical surface-guided and X-ray-guided imaging with respect to the impact on intracranial stereotactic radiotherapy.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2024Article
- Multidisciplinary management of difficult/aggressive growth-hormone pituitary neuro-endocrine tumors.Frontiers in endocrinology · 2023Review
- Management of persistent acromegaly following primary therapy: The current landscape in the UK.Endocrinology, diabetes & metabolism · 2020Review
- Efficacy and safety of fractionated conformal radiation therapy in acromegaly: a long-term follow-up study.Endocrine · 2019Article
- The Endothelium in Acromegaly.Frontiers in endocrinology · 2019Review
- Malaysian Consensus Statement for the Diagnosis and Management of Acromegaly.Journal of the ASEAN Federation of Endocrine Societies · 2019Article
- Need for improved monitoring in patients with acromegaly.Endocrine connections · 2015Review
- Treatment of acromegaly patients with risk-adapted single or fractionated stereotactic high-precision radiotherapy: High local control and low toxicity in a pooled series.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2015Article
- Complications following primary and revision transsphenoidal surgeries for pituitary tumors.The Laryngoscope · 2015Article
- Treatment of Acromegaly: Are We Satisfied With the Current Outcome?EBioMedicine · 2015Article
- Cardiovascular events in acromegaly: distinct role of Agatston and Framingham score in the 5-year prediction.Endocrine · 2014Article
- Pharmacological treatment of acromegaly: its place in the overall therapeutic approach.Journal of neuro-oncology · 2014Review
- Benign and malignant nodular thyroid disease in acromegaly. Is a routine thyroid ultrasound evaluation advisable?PloS one · 2014Article
- Radiosurgery with photons or protons for benign and malignant tumours of the skull base: a review.Radiation oncology (London, England) · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Radiotherapy (RT) remains an effective treatment in patients with acromegaly refractory to medical and/or surgical interventions, with durable tumor control and biochemical remission; however, there are still concerns about delayed biochemical effect and potential late toxicity of radiation treatment, especially high rates of hypopituitarism. Stereotactic radiotherapy has been developed as a more accurate technique of irradiation with more precise tumour localization and consequently a reduction in the volume of normal tissue, particularly the brain, irradiated to high radiation doses. Radiation can be delivered in a single fraction by stereotactic radiosurgery (SRS) or as fractionated stereotactic radiotherapy (FSRT) in which smaller doses are delivered over 5-6 weeks in 25-30 treatments. A review of the recent literature suggests that pituitary irradiation is an effective treatment for acromegaly. Stereotactic techniques for GH-secreting pituitary tumors are discussed with the aim to define the efficacy and potential adverse effects of each of these techniques.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.