ArticleBMC cardiovascular disorders2011
The higher exercise intensity and the presence of allele I of ACE gene elicit a higher post-exercise blood pressure reduction and nitric oxide release in elderly women: an experimental study.
Article in BMC cardiovascular disorders, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- Acute Effects of Exercise on Blood Pressure: A Meta-Analytic Investigation.Arquivos brasileiros de cardiologia · 2016Pooled it
- Effect of exercise training on the renin-angiotensin-aldosterone system in healthy individuals: a systematic review and meta-analysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2016Pooled it
- Efficacy of Unsupervised YouTube Dance Exercise for Patients With Hypertension: Randomized Controlled Trial.JMIR cardio · 2025Trial
- Post-Exercise Hypotension and Its Mechanisms Differ after Morning and Evening Exercise: A Randomized Crossover Study.PloS one · 2015Trial
- Association of cardiovascular response to an acute resistance training session with the ACE gene polymorphism in sedentary women: a randomized trial.BMC cardiovascular disorders · 2013Trial
- Combined exercise circuit session acutely attenuates stress-induced blood pressure reactivity in healthy adults.Brazilian journal of physical therapyTrial
- Effects of 12-week aquatic HIIT on blood pressure lipid profile and BaPWV in postmenopausal women with different ACE genotypes.Scientific reports · 2026Article
- Association between Angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism on the susceptibility to psoriasis and oxidative stress (OS) in a cohort of pediatric psoriatic patients in Sri Lanka: A cross sectional study.Health science reports · 2024Article
- Association between ComplexGenes · 2024Article
- Review
- Effects of Acute Aquatic High-Intensity Intermittent Exercise on Blood Pressure and Arterial Stiffness in Postmenopausal Women with Different ACE Genotypes.International journal of environmental research and public health · 2022Article
- The Effect of Exercise on the Older Adult's Blood Pressure Suffering Hypertension: Systematic Review and Meta-Analysis on Clinical Trial Studies.International journal of hypertension · 2020Article
- Review
- Correlations betweenBioscience reports · 2017Article
- Contact Karate Promotes Post-Exercise Hypotension in Young Adult Males.Asian journal of sports medicine · 2016Article
- Understanding the responsiveness of nitric oxide to acute eccentric resistance exercise in elderly obese women.Journal of clinical and translational research · 2016Article
- Central and peripheral pathogenetic forms of type 2 diabetes: a proof-of-concept study.Endocrine connections · 2016Article
- Intensity of swimming exercise influences aortic reactivity in rats.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2015Article
- Role of SIRT3 in Angiotensin II-induced human umbilical vein endothelial cells dysfunction.BMC cardiovascular disorders · 2015Article
- Blood pressure changes following aerobic exercise in Caucasian and Chinese descendants.International journal of sports medicine · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe absence of the I allele of the angiotensin converting enzyme (ACE) gene has been associated with higher levels of circulating ACE, lower nitric oxide (NO) release and hypertension. The purposes of this study were to analyze the post-exercise salivary nitrite (NO2-) and blood pressure (BP) responses to different exercise intensities in elderly women divided according to their ACE genotype.
methodsParticipants (n = 30; II/ID = 20 and DD = 10) underwent three experimental sessions: incremental test - IT (15 watts workload increase/3 min) until exhaustion; 20 min exercise 90% anaerobic threshold (90% AT); and 20 min control session without exercise. Volunteers had their BP and NO2- measured before and after experimental sessions.
resultsDespite both intensities showed protective effect on preventing the increase of BP during post-exercise recovery compared to control, post-exercise hypotension and increased NO2- release was observed only for carriers of the I allele (p < 0.05).
conclusionGenotypes of the ACE gene may exert a role in post-exercise NO release and BP response.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.