ArticleStroke research and treatment2012
Is Near-Infrared Spectroscopy a Reliable Method to Evaluate Clamping Ischemia during Carotid Surgery?
Article in Stroke research and treatment, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 45 citations in OpenAlex.
- Alveolar Recruitment Maneuver Reduces Cerebral Oxygen Saturation and Cerebral Blood Flow Velocity in Patients During Carotid Endarterectomy.Medical science monitor : international medical journal of experimental and clinical research · 2021Trial
- Correlation Between End-Tidal Carbon Dioxide and Regional Cerebral Oxygen Saturation During Cardiopulmonary Resuscitation.Journal of clinical medicine · 2025Article
- Non-Invasive Tools in Perioperative Stroke Risk Assessment for Asymptomatic Carotid Artery Stenosis with a Focus on the Circle of Willis.Journal of clinical medicine · 2024Review
- Near-Infrared Spectroscopy-Guided, Individualized Arterial Blood Pressure Management for Carotid Endarterectomy under General Anesthesia: A Randomized, Controlled Trial.Journal of clinical medicine · 2023Article
- Intraoperative monitoring of cerebrovascular autoregulation in infants and toddlers receiving major elective surgery to determine the individually optimal blood pressure - a pilot study.Frontiers in pediatrics · 2023Article
- Intraoperative Cerebral Hemodynamic Monitoring during Carotid Endarterectomy via Diffuse Correlation Spectroscopy and Near-Infrared Spectroscopy.Brain sciences · 2022Article
- Anesthetic management of carotid endarterectomy: an update from Italian guidelines.Journal of anesthesia, analgesia and critical care · 2022Article
- Association between the reactivity of local cerebral oxygen saturation after hypo-to-hypercapnic tests and delirium after abdominal surgery in older adults: A prospective study.Frontiers in psychiatry · 2022Article
- Regional cerebral oxygen saturation and postoperative delirium in endovascular surgery: a prospective cohort study.Trials · 2019Observational
- The Efficacy of Near-Infrared Spectroscopy Monitoring in Carotid Endarterectomy: A Prospective, Single-Center, Observational Study.Cell transplantation · 2019Observational
- Cerebrovascular Disease and Perioperative Neurologic Vulnerability: A Prospective Cohort Study.Frontiers in neurology · 2019Article
- Monitoring cerebral ischemia during carotid endarterectomy and stenting.Journal of biomedical research · 2017Review
- Damage control management of innominate artery injury with tracheostomy.Surgical case reports · 2016Article
- Anesthetic approaches in carotid body tumor surgery.Northern clinics of Istanbul · 2016Article
- Cerebral oxygenation and processed EEG response to clamping and shunting during carotid endarterectomy under general anesthesia.Journal of clinical monitoring and computing · 2015Observational
- Systematic review of near-infrared spectroscopy determined cerebral oxygenation during non-cardiac surgery.Frontiers in physiology · 2014Review
- Temporal hemodynamic classification of two hands tapping using functional near-infrared spectroscopy.Frontiers in human neuroscience · 2013Article
- General versus local anesthesia for carotid endarterectomy: Special considerations.Saudi journal of anaesthesiaReview
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Guidelines do not include cerebral oximetry among monitoring for carotid endarterectomy (CEA). The purpose of this study was to evaluate the reliability of near-infrared spectroscopy (NIRS) in the detection of clamping ischemia and in the prevention of clamping-related neurologic deficits using, as a cutoff for shunting, a 20% regional cerebral oxygen saturation (rSO(2)) decrease if persistent more than 4 minutes, otherwise a 25% rSO(2) decrease. Bilateral rSO(2) was monitored continuously in patients undergoing CEA under general anesthesia (GA). Data was recorded after clamping, declamping, during shunting and lowest values achieved. Preoperative neurologic, CT-scan, and vascular lesions were recorded. We reviewed 473 cases: 305 males (64.5%) mean age 73.3 ± 7.3. Three patients presented transient ischemic deficits at awakening, no perioperative stroke or death; 41 (8.7%) required shunting: 30 based on the initial rSO(2) value and 11 due to a decrease during surgery. Using the ROC curve analysis we found, for a >25% reduction from baseline value, a sensitivity of 100% and a specificity of 90.6%. Reliability, PPV, and NPV were 95.38%, 9%, and 100%, respectively. In conclusion, this study indicates the potential reliability of NIRS monitoring during CEA under GA, using a cutoff of 25% or a cutoff of 20% for prolonged hypoperfusion.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.