ArticleJournal of clinical microbiology2012
Complete genome and clinicopathological characterization of a virulent Newcastle disease virus isolate from South America.
Article in Journal of clinical microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
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Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it, 107 citations in OpenAlex.
- Epidemiology of Newcastle disease in chickens of Ethiopia: a systematic review and meta-analysis.Tropical animal health and production · 2022Pooled it
- Prevalence, molecular characterization and phylogenetic analysis of Newcastle disease virus isolated from domestic poultry during 2019-2024 in Egypt.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
- Immunogenetic insights into matching bivalent inactivated Payavax G79® for sustainable poultry vaccination against NDV-GVII and H9N2.Archives of virology · 2025Article
- Long-term surveillance of avian avulavirus in wild birds in China from 2003 to 2020.Virologica Sinica · 2025Article
- Genetic Diversity of Newcastle Disease Virus and Its Implications for Vaccine Development.Veterinary sciences · 2025Review
- Detection and differentiation of low virulence and virulent Orthoavulavirus javaense using a molecular beacon with RT-LAMP.Scientific reports · 2024Article
- Genetic Diversity of Newcastle Disease Virus Involved in the 2021 Outbreaks in Backyard Poultry Farms in Tanzania.Veterinary sciences · 2023Article
- Article
- Phylogeny and Pathogenicity of Subtype XIIb NDVs from Francolins in Southwestern China and Effective Protection by an Inactivated Vaccine.Transboundary and emerging diseases · 2023Article
- Intranasal vaccination of hamsters with a Newcastle disease virus vector expressing the S1 subunit protects animals against SARS-CoV-2 disease.Scientific reports · 2022Article
- Article
- Review detection of Newcastle disease virus.Frontiers in veterinary science · 2022Review
- Article
- Newcastle Disease in Backyard Poultry Rearing in the Northeastern States of India: Challenges and Control Strategies.Frontiers in veterinary science · 2022Article
- A Pigeon-Derived Sub-Genotype XXI.1.2 Newcastle Disease Virus from Bangladesh Induces High Mortality in Chickens.Viruses · 2021Article
- Avian Viruses that Impact Table Egg Production.Animals : an open access journal from MDPI · 2020Review
- Evolutionary Dynamics and Age-Dependent Pathogenesis of Sub-Genotype VI.2.1.1.2.2 PPMV-1 in Pigeons.Viruses · 2020Article
- Protective efficacy of the Newcastle disease virus genotype VII-matched vaccine in commercial layers.Poultry science · 2020Article
- Rapid Development of an Effective Newcastle Disease Virus Vaccine Candidate by Attenuation of a Genotype VII Velogenic Isolate Using a Simple Infectious Cloning System.Frontiers in veterinary science · 2020Article
- Efficacy of inactivated velogenic Newcastle disease virus genotype VII vaccine in broiler chickens.Veterinary research forum : an international quarterly journal · 2020Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Newcastle disease (ND) is one of the most important diseases of poultry, negatively affecting poultry production worldwide. The disease is caused by Newcastle disease virus (NDV) or avian paramyxovirus type 1 (APMV-1), a negative-sense single-stranded RNA virus of the genus Avulavirus, family Paramyxoviridae. Although all NDV isolates characterized to date belong to a single serotype of APMV-1, significant genetic diversity has been described between different NDV isolates. Here we present the complete genome sequence and the clinicopathological characterization of a virulent Newcastle disease virus isolate (NDV-Peru/08) obtained from poultry during an outbreak of ND in Peru in 2008. Phylogenetic reconstruction and analysis of the evolutionary distances between NDV-Peru/08 and other isolates representing established NDV genotypes revealed the existence of large genomic and amino differences that clearly distinguish this isolate from viruses of typical NDV genotypes. Although NDV-Peru/08 is a genetically distinct virus, pathogenesis studies conducted with chickens revealed that NDV-Peru/08 infection results in clinical signs characteristic of velogenic viscerotropic NDV strains. Additionally, vaccination studies have shown that an inactivated NDV-LaSota/46 vaccine conferred full protection from NDV-Peru/08-induced clinical disease and mortality. This represents the first complete characterization of a virulent NDV isolate from South America.
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