Evidence map›Paper›PMID 22135235›Full record

ReviewJournal of cellular biochemistry2012

Control of mitochondrial activity by miRNAs.

Peifeng Li, Jianqing Jiao, Guifeng Gao, Bellur S Prabhakar

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of cellular biochemistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 140 citations in OpenAlex.

  1. Review
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  15. Review
  16. Mitochondrial microRNAs Are Dysregulated in Patients with Fabry Disease.The Journal of pharmacology and experimental therapeutics · 2023
    Article
  17. Review
  18. Skeletal muscle MiR-210 expression is associated with mitochondrial function in peripheral artery disease patients.Translational research : the journal of laboratory and clinical medicine · 2022
    Article
  19. Review
  20. miRNAs: The Key Regulator of COVID-19 Disease.International journal of cell biology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Peifeng LiDepartment of Microbiology and Immunology, College of Medicine, University of Illinois at Chicago, Chicago, Illinois 60612, USA.
Jianqing Jiao
Guifeng Gao
Bellur S Prabhakar
Chinese Academy of Sciences · CNUniversity of Illinois Chicago · US

Funding

Role of mitochondria in cardiac ischemiaR01HL102202 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LI, PEIFENG · 2011 to 2015
$1.5M
Novel human gene-IG20-potential role in cancer therapyR01CA107506 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI PRABHAKAR, BELLUR S · 2005 to 2009
$1.3M
A novel anti-hypertrophic pathway in the heartR21HL092315 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LI, PEIFENG · 2009 to 2010
$431k
NCI NIH HHS 5R01CA107506NCI NIH HHS R01 CA107506NHLBI NIH HHS 1R01HL102202NHLBI NIH HHS 5R21HL092315NHLBI NIH HHS R01 HL102202NHLBI NIH HHS R21 HL092315
6 · The paper itself

Abstract

Mitochondria supply energy for physiological function and they participate in the regulation of other cellular events including apoptosis, calcium homeostasis, and production of reactive oxygen species. Thus, mitochondria play a critical role in the cells. However, dysfunction of mitochondria is related to a variety of pathological processes and diseases. MicroRNAs (miRNAs) are a class of small noncoding RNAs about 22 nucleotides long, and they can bind to the 3'-untranslated region (3'-UTR) of mRNAs, thereby inhibiting mRNA translation or promoting mRNA degradation. We summarize the molecular regulation of mitochondrial metabolism, structure, and function by miRNAs. Modulation of miRNAs levels may provide a new therapeutic approach for the treatment of mitochondria-related diseases.

Indexed as

3' Untranslated RegionsAnimalsApoptosisHumansMicroRNAsMitochondria3' Untranslated RegionsMicroRNAs

Identifiers

PMID22135235
PMCPMC3325319
OpenAlexW1970938389

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.