Evidence map›Paper›PMID 22134936›Full record

Trial reportMayo Clinic proceedings2011

Population screening for barrett esophagus: a prospective randomized pilot study.

Joseph Y Chang, Nicholas J Talley, G Richard Locke, David A Katzka, Cathy D Schleck, Alan R Zinsmeister, Kelly T Dunagan, Tsung-Teh Wu, Kenneth K Wang, Ganapathy A Prasad

2 registry-linked trialsAbstract readComparative StudyRandomized Controlled TrialVideo-Audio Media
In one paragraph

Trial report in Mayo Clinic proceedings, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00943280 completednot on this map

Population Based Screening for Barrett's Esophagus in Olmsted County : A Pilot Study

TypeobservationalSponsorMayo ClinicRan2009 to 2010Enrolled60ConditionsBarrett's Esophagus
NCT03167970 completednot on this mapstarted 2017, after this paper: background citation

Evaluation of Performance Characteristics of Capsule Endoscopy With PillCam UGI Capsule Compared to Standard Endoscopy for Screening of Barrett's Esophagus: A Prospective Tandem Study

TypeobservationalSponsorMidwest Biomedical ResearchRan2017 to 2018Enrolled21ConditionsBarrett EsophagusArmsPill cam, EGD
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline on screening for esophageal adenocarcinoma in patients with chronic gastroesophageal reflux disease.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2020
    Guideline
  2. ACG Clinical Guideline: Diagnosis and Management of Barrett's Esophagus.The American journal of gastroenterology · 2016
    Guideline
  3. Cost analysis of office-based transnasal esophagoscopy.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2019
    Trial
  4. Trial
  5. Trial
  6. Trial
  7. Article
  8. Article
  9. Article
  10. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2020
    Article
  11. Article
  12. Review
  13. Recent Advances in Screening for Barrett's Esophagus.Current treatment options in gastroenterology · 2018
    Review
  14. Screening for Barrett's esophagus and esophageal adenocarcinoma: rationale, recent progress, challenges, and future directions.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2015
    Review
  15. Review
  16. Review
  17. Management strategies of Barrett's esophagus.World journal of gastroenterology · 2012
    Review
  18. Diagnosis and management of Barrett's esophagus.The Surgical clinics of North America · 2012
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Joseph Y ChangDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, USA. prasad.ganapathy@mayo.edu
Nicholas J Talley
G Richard Locke
David A Katzka
Cathy D Schleck
Alan R Zinsmeister
Kelly T Dunagan
Tsung-Teh Wu
Kenneth K Wang
Ganapathy A Prasad

Funding

MAYO CLINIC CENTER FOR TRANSLATIONAL SCIENCE ACTIVITIESUL1RR024150 · NCRR · MAYO CLINIC ROCHESTER · PI RIZZA, ROBERT A. · 2006 to 2011
$66.4M
Rochester Epidemiology ProjectR01AG034676 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2010 to 2019
$9.5M
Comparative Effectiveness of endoscopic assessment of GER and BERC4DK090413 · NIDDK · MAYO CLINIC ROCHESTER · PI IYER, PRASAD G. · 2010 to 2012
$1.0M
NCRR NIH HHS UL1 RR024150NIA NIH HHS R01 AG034676NIDDK NIH HHS RC4 DK090413NIDDK NIH HHS RC4DK090413
6 · The paper itself

Abstract

objectiveTo assess the feasibility of unsedated transnasal endoscopy (uTNE) and video capsule endoscopy (VCE) as alternatives to sedated endoscopy (sEGD) as screening tools for Barrett esophagus (BE) and to obtain preliminary estimates of participation rates for sEGD, uTNE, and VCE when used for community BE screening in a population cohort. PATIENTS AND

methodsFrom February 1, 2009, to May 31, 2010, patients from Olmsted County, Minnesota, who were older than 50 years and had no history of known BE were randomized (stratified by age, sex, reflux symptoms noted in a validated questionnaire) into 3 groups for esophageal evaluation with sEGD, uTNE, or VCE. Participation rates and safety profiles were estimated.

resultsWe contacted 127 patients to recruit 20 for each procedure arm (60 total). The probability of participation was 38% (95% confidence interval [CI], 26%-51%) for sEGD, 50% (95% CI, 35%-65%) for uTNE, and 59% (95% CI, 42%-74%) for VCE. Both uTNE and VCE were well tolerated without adverse effects. BE was identified in 3 patients and esophagitis in 8.

conclusionUnsedated techniques may be acceptable, feasible, and safe alternatives to sEGD to screen for BE in the community.

trial registrationclinicaltrials.gov identifier: NCT00943280.

Indexed as

Barrett EsophagusCapsule EndoscopyEndoscopy, GastrointestinalFeasibility StudiesFemaleFollow-Up StudiesHumansIncidenceMaleMass ScreeningMiddle AgedMinnesotaPilot ProjectsProspective StudiesReproducibility of Results

Identifiers

PMID22134936
PMCPMC3228617

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.