ArticleMolecules and cells2012
Leaf variegation in the rice zebra2 mutant is caused by photoperiodic accumulation of tetra-cis-lycopene and singlet oxygen.
Article in Molecules and cells, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- The C2H2-type zinc finger protein ZOS202 regulates leaf senescence in rice by targeting senescence-associated transcription factors and ROS homoeostasis.The Plant journal : for cell and molecular biology · 2026Article
- Genome-wide association study uncovers a novel gene responsible for rice seedling submergence tolerance.Plant biotechnology journal · 2025Article
- Transcriptomic and Structural Insights into Leaf Variegation Development inInternational journal of molecular sciences · 2025Article
- ABA and Pre-Harvest Sprouting Differences in Knockout Lines of OsPHS3 Encoding Carotenoid Isomerase via CRISPR/Cas9 in Rice.Plants (Basel, Switzerland) · 2025Article
- Mutation ofInternational journal of molecular sciences · 2022Article
- LSL1 controls cell death and grain production by stabilizing chloroplast in rice.Science China. Life sciences · 2022Article
- AeLife · 2020Article
- Zebra leaf 15, a receptor-like protein kinase involved in moderate low temperature signaling pathway in rice.Rice (New York, N.Y.) · 2019Article
- Protective Role of Leaf Variegation inInternational journal of molecular sciences · 2019Article
- Mutagenesis in Rice: The Basis for Breeding a New Super Plant.Frontiers in plant science · 2019Review
- The rice zebra3 (z3) mutation disrupts citrate distribution and produces transverse dark-green/green variegation in mature leaves.Rice (New York, N.Y.) · 2018Article
- Identification and Phenotypic Characterization ofFrontiers in plant science · 2018Article
- Two NADPH: Protochlorophyllide Oxidoreductase (POR) Isoforms Play Distinct Roles in Environmental Adaptation in Rice.Rice (New York, N.Y.) · 2017Article
- Rice 7-Hydroxymethyl ChlorophyllMolecules and cells · 2017Article
- Rice Phytochrome-Interacting Factor-Like1 (OsPIL1) is involved in the promotion of chlorophyll biosynthesis through feed-forward regulatory loops.Journal of experimental botany · 2017Article
- Ascribing Functions to Genes: Journey Towards Genetic Improvement of Rice Via Functional Genomics.Current genomics · 2016Article
- Mutation of SPOTTED LEAF3 (SPL3) impairs abscisic acid-responsive signalling and delays leaf senescence in rice.Journal of experimental botany · 2015Article
- OsWRKY42 represses OsMT1d and induces reactive oxygen species and leaf senescence in rice.Molecules and cells · 2014Article
- Mapped clone and functional analysis of leaf-color gene Ygl7 in a rice hybrid (Oryza sativa L. ssp. indica).PloS one · 2014Article
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4 authors.
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Abstract
In field conditions, the zebra2 (z2) mutant in rice (Oryza sativa) produces leaves with transverse pale-green/yellow stripes. It was recently reported that ZEBRA2 encodes carotenoid isomerase (CRTISO) and that low levels of lutein, an essential carotenoid for non-photochemical quenching, cause leaf variegation in z2 mutants. However, we found that the z2 mutant phenotype was completely suppressed by growth under continuous light (CL; permissive) conditions, with concentrations of chlorophyll, carotenoids and chloroplast proteins at normal levels in z2 mutants under CL. In addition, three types of reactive oxygen species (ROS; superoxide [O₂⁻], hydrogen peroxide [H₂O₂], and singlet oxygen [¹O₂]) accumulated to high levels in z2 mutants grown under short-day conditions (SD; alternate 10-h light/14-h dark; restrictive), but do not accumulate under CL conditions. However, the levels of lutein and zeaxanthin in z2 leaves were much lower than normal in both permissive CL and restrictive SD growth conditions, indicating that deficiency of these two carotenoids is not responsible for the leaf variegation phenotype. We found that the CRTISO substrate tetra-Cis-lycopene accumulated during the dark periods under SD, but not under CL conditions. Its accumulation was also positively correlated with ¹O₂ levels generated during the light period, which consequently altered the expression of ¹O₂-responsive and cell death-related genes in the variegated z2 leaves. Taking these results together, we propose that the z2 leaf variegation can be largely attributed to photoperiodic accumulation of tetra-cis-lycopene and generation of excessive ¹O₂ under natural day-night conditions.
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