ArticleMolecules (Basel, Switzerland)2011
Protective effect of salidroside from Rhodiolae Radix on diabetes-induced oxidative stress in mice.
Article in Molecules (Basel, Switzerland), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed.
- Salidroside attenuates diabetic retinopathy by upregulating miR-142-3p to target TRAF6.Journal of molecular histology · 2026Article
- Salidroside and inflammation-linked disorders: integrative insights into the pharmacological effects and mechanistic targets.Inflammopharmacology · 2025Review
- Exploring the Therapeutic Potential ofCurrent issues in molecular biology · 2025Article
- The Antioxidant Salidroside Ameliorates the Quality of Postovulatory Aged Oocyte and Embryo Development in Mice.Antioxidants (Basel, Switzerland) · 2024Article
- Article
- Phenolic Compounds ofInternational journal of molecular sciences · 2023Review
- Pharmacological functions of salidroside in renal diseases: facts and perspectives.Frontiers in pharmacology · 2023Review
- Article
- Discovery of human pancreatic lipase inhibitors from root ofJournal of pharmaceutical analysis · 2022Article
- Salidroside Ameliorates Ultraviolet-Induced Keratinocyte Injury by Inducing SIRT1-Dependent Autophagy.Clinical, cosmetic and investigational dermatology · 2022Article
- Phenolic Compounds fromMolecules (Basel, Switzerland) · 2021Article
- Chinese Herbal Medicines and Active Metabolites: Potential Antioxidant Treatments for Atherosclerosis.Frontiers in pharmacology · 2021Review
- Neuroprotective Effect of Syringic Acid by Modulation of Oxidative Stress and Mitochondrial Mass in Diabetic Rats.BioMed research international · 2020Article
- Beneficial Effects of Rhodiola and Salidroside in Diabetes: Potential Role of AMP-Activated Protein Kinase.Molecular diagnosis & therapy · 2019Review
- Salidroside ameliorates Adriamycin nephropathy in mice by inhibiting β-catenin activity.Journal of cellular and molecular medicine · 2019Article
- α-Amylase and α-glucosidase inhibitor effects and pancreatic response to diabetes mellitus on Wistar rats of Ephedra alata areal part decoction with immunohistochemical analyses.Environmental science and pollution research international · 2019Article
- Rosenroot (Aging and disease · 2019Review
- Salidroside Improves Bone Histomorphology and Prevents Bone Loss in Ovariectomized Diabetic Rats by Upregulating the OPG/RANKL Ratio.Molecules (Basel, Switzerland) · 2018Article
- Salidroside Protects Against Advanced Glycation End Products-Induced Vascular Endothelial Dysfunction.Medical science monitor : international medical journal of experimental and clinical research · 2018Article
- Time-dependent effects of late-onset dietary intake of salidroside on lifespan and age-related biomarkers of the annual fishOncotarget · 2018Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It has been confirmed that diabetes mellitus (DM) carries increased oxidative stress. This study evaluated the effects of salidroside from Rhodiolae Radix on diabetes-induced oxidative stress in mice. After induction of diabetes, diabetic mice were administered daily doses of 50, 100 and 200 mg/kg salidroside for 28 days. Body weights, fasting blood glucose (FBG), serum insulin, TC (total cholesterol), TG (triglyceride), malondialdehyde (MDA), superoxide dismutase (SOD), glutathione peroxidase (GPx) and catalase (CAT) were measured. Results showed that salidroside possessed hypoglycemic activity and protective effects against diabetes-induced oxidative stress, which could significantly reduce FBG, TC, TG and MDA levels, and at same time increase serum insulin levels, SOD, GPx and CAT activities. Therefore, salidroside should be considered as a candidate for future studies on diabetes.
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Registered trials
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