Evidence map›Paper›PMID 22134175›Full record

Trial reportJournal of addiction medicine2012

Impact of methadone with versus without drug abuse counseling on HIV risk: 4- and 12-month findings from a clinical trial.

Sharon M Kelly, Robert P Schwartz, Kevin E Oʼgrady, Devang Gandhi, Jerome H Jaffe

2 registry-linked trialsAbstract readComparative StudyMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of addiction medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00712036 nacompletednot on this map

Entry Into Comprehensive Methadone Treatment Via Interim Maintenance

TypeinterventionalSponsorFriends Research Institute, Inc.Ran2008 to 2011Enrolled230ConditionsOpiate DependenceArmsInterim, Comprehensive, Restored
NCT06581276 nacompletednot on this mapstarted 2023, after this paper: background citation

Increasing Access to Evidence-based Treatment for Chronic Pain and Opioid Use Disorder: Adapting Acceptance and Commitment Therapy for Opioid Treatment Programs

TypeinterventionalSponsorMontefiore Medical CenterRan2023 to 2024Enrolled7ConditionsOpioid Use, Opioid Use Disorder, Chronic PainArmsAcceptance and Commitment Therapy (ACT)
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Pooled it
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  4. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sharon M KellyFriends Research Institute, Baltimore, MD 21201, USA. skelly@friendsresearch.org
Robert P Schwartz
Kevin E Oʼgrady
Devang Gandhi
Jerome H Jaffe
Jacobson Holman (United States) · US

Funding

Services Research on Interim Opioid MaintenanceR01DA013636 · NIDA · FRIENDS RESEARCH INSTITUTE, INC. · PI SCHWARTZ, ROBERT P · 2001 to 2010
$3.1M
NIDA NIH HHS 2R01 DA13636NIDA NIH HHS R01 DA013636
6 · The paper itself

Abstract

objectiveHuman immunodeficiency virus (HIV)-risk behaviors were examined at 4- and 12-month follow-up for 230 newly admitted methadone patients randomly assigned to receive either methadone only (n = 99) or methadone with drug abuse counseling (n = 131) in the first 4 months of treatment.

methodsThe AIDS Risk Assessment was administered at baseline (treatment entry) and at 4- and 12-month follow-up. Linear mixed model analysis examined changes in HIV drug- and sex-risk behaviors over the 12 months in the total sample, drug-risk behaviors in the subsample that reported injecting drugs at baseline (n = 110), and sex-risk behaviors in the subsample that reported engaging in unprotected sex at baseline (n = 130).

resultsSignificant decreases over time were found in the frequencies of injecting, injecting with other injectors, and sharing cooker, cotton, or rinse water in the total sample and the injector subsample (P < 0.05). Decreases were also found in the frequencies of having sex without a condom either with someone who was not a spouse or primary partner or while high (P < 0.05) in the total sample and the frequencies of having sex without a condom and having sex without a condom while high in the unprotected-sex subsample (P < 0.05). No significant treatment group main effects or Treatment Group × Time interaction effects were found in any of the HIV-risk behaviors in the total sample or either subsample (P > 0.05).

conclusionsDuring the first 12 months of treatment, providing drug abuse counseling with methadone compared with providing methadone alone was not associated with significant changes in HIV-risk behaviors for methadone maintenance patients.

Indexed as

CounselingOpiate Substitution TreatmentAdultBaltimoreCombined Modality TherapyCrisis InterventionDose-Response Relationship, DrugFemaleFollow-Up StudiesHealth Knowledge, Attitudes, PracticeHeroin DependenceHIV InfectionsHumansMaleMethadoneMiddle AgedMethadoneNarcotics

Identifiers

PMID22134175
PMCPMC3322294
OpenAlexW2039071306

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.