ArticleThe Journal of asthma : official journal of the Association for the Care of Asthma2012
Noninvasive testing of lung function and inflammation in pediatric patients with acute asthma exacerbations.
Article in The Journal of asthma : official journal of the Association for the Care of Asthma, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 15 citations in OpenAlex.
- Monitoring respiratory function with telemedicine devices in asthmatic children.Frontiers in medicine · 2025Article
- Single Breath Counting for Diagnosis and Prediction of Severity of Acute Asthma Exacerbation in Children.Indian journal of pediatrics · 2023Observational
- Defining Treatment Response for Clinical Trials of Pediatric Acute Asthma.The journal of allergy and clinical immunology. In practice · 2023Article
- Emergency department treatment of asthma in children: A review.Journal of the American College of Emergency Physicians open · 2020Review
- Oscillometry for acute asthma in the pediatric emergency department: A feasibility study.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2020Article
- Forced expiratory values in 1 second corresponding to Pediatric Respiratory Assessment Measure and Acute Asthma Intensity Research Score values during pediatric acute asthma exacerbations.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2017Article
- Count on It! Accurately Measured Respiratory Rate Is Associated with Lung Function and Clinical Severity in Children with Acute Asthma Exacerbations.The Journal of pediatrics · 2016Article
- AAIRS Score Overview: The Acute Asthma Intensity Research Score.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2015Article
- Mycoplasma pneumonia infection and asthma: A clinical study.Pakistan journal of medical sciences · 2015Article
- Spirometry and PRAM severity score changes during pediatric acute asthma exacerbation treatment in a pediatric emergency department.The Journal of asthma : official journal of the Association for the Care of Asthma · 2013Article
- Development and internal validation of a pediatric acute asthma prediction rule for hospitalization.The journal of allergy and clinical immunology. In practiceArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
objectiveThere is limited information on performance rates for tests of lung function and inflammation in pediatric patients with acute asthma exacerbations. We sought to examine how frequently pediatric patients with acute asthma exacerbations could perform noninvasive lung function and exhaled nitric oxide (FE(NO)) testing and participant characteristics associated with successful performance.
methodsWe studied a prospective convenience sample aged 5-17 years with acute asthma exacerbations in a pediatric emergency department. Participants attempted spirometry for percent predicted forced expiratory volume in 1 second (%FEV(1)), airway resistance (Rint), and FE(NO) testing before treatment. We examined overall performance rates and the associations of age, gender, race, and baseline acute asthma severity score with successful test performance.
resultsAmong 573 participants, age was (median [interquartile range]) 8.8 [6.8, 11.5] years, 60% were male, 57% were African-American, and 58% had Medicaid insurance. Tests were performed successfully by the following [n (%)]: full American Thoracic Society-European Respiratory Society criteria spirometry, 331 (58%); Rint, 561 (98%); and FE(NO), 354 (70% of 505 attempted test). Sixty percent with mild-moderate exacerbations performed spirometry compared to 17% with severe exacerbations (p = .0001). Participants aged 8-12 years (67%) were more likely to perform spirometry than those aged 5-7 years (48%) (OR = 2.23, 95% CI: 1.45-3.11) or 13-17 years (58%) (OR = 1.61, 95% CI: 1.00-2.59).
conclusionsThere is clinically important variability in performance of these tests during acute asthma exacerbations. The proportion of patients with severe exacerbations able to perform spirometry (17%) limits its utility. Almost all children with acute asthma can perform Rint testing, and further development and validation of this technology is warranted.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.