ArticlePloS one2011
Microarray-based transcriptomic analysis of differences between long-term gregarious and solitarious desert locusts.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 53 citations in OpenAlex.
- A systematic review of locust phase polyphenism: from proximate mechanisms to ecology and management.PeerJ · 2026Pooled it
- Rapid behavioural gregarization in the desert locust, Schistocerca gregaria entails synchronous changes in both activity and attraction to conspecifics.Journal of insect physiology · 2014Pooled it
- The Integrative Imperatives of Locust Phase Polyphenism Research: A Bibliometric Analysis.Integrative organismal biology (Oxford, England) · 2026Review
- Article
- Contribution of Epigenetic Mechanisms in the Regulation of Environmentally-Induced Polyphenism in Insects.Insects · 2021Review
- Comparative analysis of phenotypic plasticity sheds light on the evolution and molecular underpinnings of locust phase polyphenism.Scientific reports · 2021Article
- Social modulation of ageing: mechanisms, ecology, evolution.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
- Article
- SEGN: Inferring real-time gene networks mediating phenotypic plasticity.Computational and structural biotechnology journal · 2020Article
- Transcriptome analysis of a social caterpillar, Drepana arcuata: De novo assembly, functional annotation and developmental analysis.PloS one · 2020Article
- Environmental and Evolutionary Drivers of the Modular Gene Regulatory Network Underlying Phenotypic Plasticity for Stress Resistance in the NematodeG3 (Bethesda, Md.) · 2019Article
- RNA-Seq reveals large quantitative differences between the transcriptomes of outbreak and non-outbreak locusts.Scientific reports · 2018Article
- Evolution, expression and association of the chemosensory protein genes with the outbreak phase of the two main pest locusts.Scientific reports · 2017Article
- Cortical spreading depression-induced preconditioning in the brain.Neural regeneration research · 2016Review
- Differential Gene Expression Analysis of the Epacromius coerulipes (Orthoptera: Acrididae) Transcriptome.Journal of insect science (Online) · 2016Article
- We can't all be supermodels: the value of comparative transcriptomics to the study of non-model insects.Insect molecular biology · 2015Review
- Na+-K+-ATPase trafficking induced by heat shock pretreatment correlates with increased resistance to anoxia in locusts.Journal of neurophysiology · 2014Article
- Genomics: moving behavioural ecology beyond the phenotypic gambit.Animal behaviour · 2014Article
- Ovary ecdysteroidogenic hormone functions independently of the insulin receptor in the yellow fever mosquito, Aedes aegypti.Insect biochemistry and molecular biology · 2013Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 3 countries.
Funding
Abstract
Desert locusts (Schistocerca gregaria) show an extreme form of phenotypic plasticity and can transform between a cryptic solitarious phase and a swarming gregarious phase. The two phases differ extensively in behavior, morphology and physiology but very little is known about the molecular basis of these differences. We used our recently generated Expressed Sequence Tag (EST) database derived from S. gregaria central nervous system (CNS) to design oligonucleotide microarrays and compare the expression of thousands of genes in the CNS of long-term gregarious and solitarious adult desert locusts. This identified 214 differentially expressed genes, of which 40% have been annotated to date. These include genes encoding proteins that are associated with CNS development and modeling, sensory perception, stress response and resistance, and fundamental cellular processes. Our microarray analysis has identified genes whose altered expression may enable locusts of either phase to deal with the different challenges they face. Genes for heat shock proteins and proteins which confer protection from infection were upregulated in gregarious locusts, which may allow them to respond to acute physiological challenges. By contrast the longer-lived solitarious locusts appear to be more strongly protected from the slowly accumulating effects of ageing by an upregulation of genes related to anti-oxidant systems, detoxification and anabolic renewal. Gregarious locusts also had a greater abundance of transcripts for proteins involved in sensory processing and in nervous system development and plasticity. Gregarious locusts live in a more complex sensory environment than solitarious locusts and may require a greater turnover of proteins involved in sensory transduction, and possibly greater neuronal plasticity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.