ArticleJournal of toxicology2011
Sulfurous gases as biological messengers and toxins: comparative genetics of their metabolism in model organisms.
Article in Journal of toxicology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 53 citations in OpenAlex.
- Article
- The Biological Consequences of the Knockout of Genes Involved in the Synthesis and Metabolism of HAntioxidants (Basel, Switzerland) · 2025Article
- Simultaneous activation of the hydrogen sulfide biosynthesis genes (CBS and CSE) induces sex-specific geroprotective effects in Drosophila melanogaster.Biogerontology · 2023Article
- Article
- Geroprotective potential of genetic and pharmacological interventions to endogenous hydrogen sulfide synthesis in Drosophila melanogaster.Biogerontology · 2021Article
- Overexpression ofAging · 2018Article
- Effects of N-acetyl-L-cysteine on lifespan, locomotor activity and stress-resistance of 3Aging · 2018Article
- Novel biosynthetic pathway for sulfur amino acids in Cryptococcus neoformans.Current genetics · 2018Article
- Emerging Roles of Carbonyl Sulfide in Chemical Biology: Sulfide Transporter or Gasotransmitter?Antioxidants & redox signaling · 2018Review
- SOFrontiers in chemistry · 2018Review
- An HBT-Based Near-Infrared Fluorescent Probe for Colorimetric and Ratiometric Detection of Bisulfite and its Application in Living Cells.Journal of fluorescence · 2017Article
- Hydrogen sulfide is an endogenous regulator of aging in Caenorhabditis elegans.Antioxidants & redox signaling · 2014Article
- Mitochondrial adaptations to utilize hydrogen sulfide for energy and signaling.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gasotransmitters are biologically produced gaseous signalling molecules. As gases with potent biological activities, they are toxic as air pollutants, and the sulfurous compounds are used as fumigants. Most investigations focus on medical aspects of gasotransmitter biology rather than toxicity toward invertebrate pests of agriculture. In fact, the pathways for the metabolism of sulfur containing gases in lower organisms have not yet been described. To address this deficit, we use protein sequences from Homo sapiens to query Genbank for homologous proteins in Caenorhabditis elegans, Drosophila melanogaster, and Saccharomyces cerevisiae. In C. elegans, we find genes for all mammalian pathways for synthesis and catabolism of the three sulfur containing gasotransmitters, H(2)S, SO(2) and COS. The genes for H(2)S synthesis have actually increased in number in C. elegans. Interestingly, D. melanogaster and Arthropoda in general, lack a gene for 3-mercaptopyruvate sulfurtransferase, an enzym for H(2)S synthesis under reducing conditions.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.