Evidence map›Paper›PMID 22131964›Full record

ReviewMarine drugs2011

Marine polysaccharides: a source of bioactive molecules for cell therapy and tissue engineering.

Karim Senni, Jessica Pereira, Farida Gueniche, Christine Delbarre-Ladrat, Corinne Sinquin, Jacqueline Ratiskol, Gaston Godeau, Anne-Marie Fischer, Dominique Helley, Sylvia Colliec-Jouault

Abstract readReview
In one paragraph

Review in Marine drugs, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed.

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21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Karim SenniSeadev-FermenSys SAS, Technopole Brest Iroise, 185 rue René Descartes, Plouzané 29280, France.
Jessica PereiraINSERM U765, Faculté de Pharmacie, UMR-S765, Université Paris Descartes, Sorbonne Paris Cité, 4 avenue de l'Observatoire, Paris 75006, France.
Farida GuenicheBiochemistry Department, Faculty of Dental Surgery, Paris Descartes University, Montrouge 92120, France.
Christine Delbarre-LadratLaboratory of Biotechnology and Marine Molecules, Ifremer, Rue de l'Ile d'Yeu, BP 21105, Nantes Cedex 03 44311, France.
Corinne SinquinLaboratory of Biotechnology and Marine Molecules, Ifremer, Rue de l'Ile d'Yeu, BP 21105, Nantes Cedex 03 44311, France.ORCID 0000-0002-8930-9535
Jacqueline RatiskolLaboratory of Biotechnology and Marine Molecules, Ifremer, Rue de l'Ile d'Yeu, BP 21105, Nantes Cedex 03 44311, France.
Gaston GodeauBiochemistry Department, Faculty of Dental Surgery, Paris Descartes University, Montrouge 92120, France.
Anne-Marie FischerINSERM U765, Faculté de Pharmacie, UMR-S765, Université Paris Descartes, Sorbonne Paris Cité, 4 avenue de l'Observatoire, Paris 75006, France.
Dominique HelleyINSERM U765, Faculté de Pharmacie, UMR-S765, Université Paris Descartes, Sorbonne Paris Cité, 4 avenue de l'Observatoire, Paris 75006, France.
Sylvia Colliec-JouaultLaboratory of Biotechnology and Marine Molecules, Ifremer, Rue de l'Ile d'Yeu, BP 21105, Nantes Cedex 03 44311, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The therapeutic potential of natural bioactive compounds such as polysaccharides, especially glycosaminoglycans, is now well documented, and this activity combined with natural biodiversity will allow the development of a new generation of therapeutics. Advances in our understanding of the biosynthesis, structure and function of complex glycans from mammalian origin have shown the crucial role of this class of molecules to modulate disease processes and the importance of a deeper knowledge of structure-activity relationships. Marine environment offers a tremendous biodiversity and original polysaccharides have been discovered presenting a great chemical diversity that is largely species specific. The study of the biological properties of the polysaccharides from marine eukaryotes and marine prokaryotes revealed that the polysaccharides from the marine environment could provide a valid alternative to traditional polysaccharides such as glycosaminoglycans. Marine polysaccharides present a real potential for natural product drug discovery and for the delivery of new marine derived products for therapeutic applications.

Indexed as

Cell- and Tissue-Based TherapyTissue EngineeringAlginatesAnimalsCyanobacteriaGlucuronic AcidGlycosaminoglycansHexuronic AcidsHumansOceans and SeasPolysaccharidesAlginatesfucoidanGlucuronic AcidGlycosaminoglycansHexuronic AcidsPolysaccharidesbiological activityblue biotechnologycell therapychemical modificationexopolysaccharidesmarine algaemarine bacteriastructuresulfated polysaccharidestissue engineering

Identifiers

PMID22131964
PMCPMC3225941

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.