ReviewMarine drugs2011
Biomedical exploitation of chitin and chitosan via mechano-chemical disassembly, electrospinning, dissolution in imidazolium ionic liquids, and supercritical drying.
Review in Marine drugs, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 187 citations in OpenAlex.
- Recent modifications of chitosan for adsorption applications: a critical and systematic review.Marine drugs · 2015Pooled it
- Fungal Biotechnology for Sustainable Biocomposites: From Mycelium Growth to Material Translation.Molecules (Basel, Switzerland) · 2026Review
- Designing halogen-free metal-phenolic imidazolium poly(ionic liquids) with multi-functional antibacterial, anti-inflammatory and cell proliferation properties for infected wounds.RSC medicinal chemistry · 2025Article
- Preparation, characterization and properties of three different nanomaterials either alone or loaded with nystatin or fluconazole antifungals.Scientific reports · 2022Article
- pH-Sensitive Drug Delivery System Based on Chitin Nanowhiskers-Sodium Alginate Polyelectrolyte Complex.Materials (Basel, Switzerland) · 2022Article
- Review
- Chitosan-Based Anti-Oxidation Delivery Nano-Platform: Applications in the Encapsulation of DHA-Enriched Fish Oil.Marine drugs · 2021Article
- Green Synthesized Chitosan/Chitosan Nanoforms/Nanocomposites for Drug Delivery Applications.Polymers · 2021Review
- Recent Advances in the Synthesis, Properties, and Applications of Modified Chitosan Derivatives: Challenges and Opportunities.Topics in current chemistry (Cham) · 2021Review
- Cytocompatibility of Bilayer Scaffolds Electrospun from Chitosan/Alginate-Chitin Nanowhiskers.Biomedicines · 2020Article
- Chitosan Grafted with Biobased 5-Hydroxymethyl-Furfural as Adsorbent for Copper and Cadmium Ions Removal.Polymers · 2020Article
- 3D Chitin Scaffolds of Marine Demosponge Origin for Biomimetic Mollusk Hemolymph-Associated BiomineralizationMarine drugs · 2020Article
- Modified Chitosan for Silver Recovery-Kinetics, Thermodynamic, and Equilibrium Studies.Materials (Basel, Switzerland) · 2020Article
- Synthesis of Novel Chitin Derivatives Bearing Amino Groups and Evaluation of Their Antifungal Activity.Marine drugs · 2018Article
- Biopolymer nanofibrils: structure, modeling, preparation, and applications.Progress in polymer science · 2018Article
- Electrospinning of Chitosan-Based Solutions for Tissue Engineering and Regenerative Medicine.International journal of molecular sciences · 2018Review
- Aerogels from Chitosan Solutions in Ionic Liquids.Polymers · 2017Article
- Photoactive Hybrid Catalysts Based on Natural and Synthetic Polymers: A Comparative Overview.Molecules (Basel, Switzerland) · 2017Review
- Article
- Encapsulation of Mentha Oil in Chitosan Polymer Matrix Alleviates Skin Irritation.AAPS PharmSciTech · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recently developed technology permits to optimize simultaneously surface area, porosity, density, rigidity and surface morphology of chitin-derived materials of biomedical interest. Safe and ecofriendly disassembly of chitin has superseded the dangerous acid hydrolysis and provides higher yields and scaling-up possibilities: the chitosan nanofibrils are finding applications in reinforced bone scaffolds and composite dressings for dermal wounds. Electrospun chitosan nanofibers, in the form of biocompatible thin mats and non-wovens, are being actively studied: composites of gelatin + chitosan + polyurethane have been proposed for cardiac valves and for nerve conduits; fibers are also manufactured from electrospun particles that self-assemble during subsequent freeze-drying. Ionic liquids (salts of alkylated imidazolium) are suitable as non-aqueous solvents that permit desirable reactions to occur for drug delivery purposes. Gel drying with supercritical CO(2) leads to structures most similar to the extracellular matrix, even when the chitosan is crosslinked, or in combination with metal oxides of interest in orthopedics.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.