Evidence map›Paper›PMID 22131950›Full record

ReviewMarine drugs2011

Production of bioactive secondary metabolites by marine vibrionaceae.

Maria Mansson, Lone Gram, Thomas O Larsen

Open access · goldAbstract readReview
In one paragraph

Review in Marine drugs, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 127 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Saturated Iso-Type Fatty Acids from the Marine BacteriumPharmaceuticals (Basel, Switzerland) · 2024
    Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Comparative Genomic Analyses of the GenusInternational journal of molecular sciences · 2022
    Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. The Antibiotic Andrimid Produced byFrontiers in microbiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Maria ManssonCenter for Microbial Biotechnology, Department of Systems Biology, Technical University of Denmark, Søltofts Plads 221, DK-2800 Kgs. Lyngby, Denmark.
Lone GramNational Food Institute, Technical University of Denmark, Søltofts Plads 221, DK-2800 Kgs. Lyngby, Denmark.
Thomas O LarsenCenter for Microbial Biotechnology, Department of Systems Biology, Technical University of Denmark, Søltofts Plads 221, DK-2800 Kgs. Lyngby, Denmark.
Technical University of Denmark · DKFood Research Institute · SK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteria belonging to the Vibrionaceae family are widespread in the marine environment. Today, 128 species of vibrios are known. Several of them are infamous for their pathogenicity or symbiotic relationships. Despite their ability to interact with eukaryotes, the vibrios are greatly underexplored for their ability to produce bioactive secondary metabolites and studies have been limited to only a few species. Most of the compounds isolated from vibrios so far are non-ribosomal peptides or hybrids thereof, with examples of N-containing compounds produced independent of nonribosomal peptide synthetases (NRPS). Though covering a limited chemical space, vibrios produce compounds with attractive biological activities, including antibacterial, anticancer, and antivirulence activities. This review highlights some of the most interesting structures from this group of bacteria. Many compounds found in vibrios have also been isolated from other distantly related bacteria. This cosmopolitan occurrence of metabolites indicates a high incidence of horizontal gene transfer, which raises interesting questions concerning the ecological function of some of these molecules. This account underlines the pending potential for exploring new bacterial sources of bioactive compounds and the challenges related to their investigation.

Indexed as

Anti-Bacterial AgentsEcologyGenetic VariationPhylogenyQuorum SensingSiderophoresVibrionaceaeAnti-Bacterial AgentsSiderophoresantibioticsbioactivemarine bacteriasiderophoresVibrio

Identifiers

PMID22131950
PMCPMC3225927
OpenAlexW2113885410

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.