ArticleAnnals of microbiology2011
Optimization of xylanase production by Streptomyces sp. P12-137 using response surface methodology and central composite design.
Article in Annals of microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 72 citations in OpenAlex.
- Efficient Assessment and Optimisation of Medium Components Influencing Extracellular Xylanase Production byInternational journal of molecular sciences · 2025Article
- An exploration of RSM, ANN, and ANFIS models for methylene blue dye adsorption using Oryza sativa straw biomass: a comparative approach.Scientific reports · 2025Article
- Optimization of production conditions, isolation, purification, and characterization of tannase from filamentous fungi.Folia microbiologica · 2024Article
- Optimization, purification, and characterization of xylanase production by a newly isolated Trichoderma harzianum strain by a two-step statistical experimental design strategy.Scientific reports · 2022Article
- Immobilization and Characterization of L-Asparaginase over Carbon Xerogels.Biotech (Basel (Switzerland)) · 2022Article
- Conversion of Wheat Bran to Xylanases and Dye Adsorbent byPolymers · 2021Article
- Process optimization for simultaneous production of cellulase, xylanase and ligninase byHeliyon · 2020Article
- Statistical based experimental optimization for co-production of endo-glucanase and xylanase from Bacillus sonorensis BD92 with their application in biomass saccharification.Folia microbiologica · 2019Article
- Utility of acidic xylanase of3 Biotech · 2018Article
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- Sorghum husk biomass as a potential substrate for production of cellulolytic and xylanolytic enzymes by Nocardiopsis sp. KNU.3 Biotech · 2017Article
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- Partial Optimization of Endo-1, 4-Β-Xylanase Production by Aureobasidium pullulans Using Agro-Industrial Residues.Iranian journal of basic medical sciences · 2013Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Response surface methodology and central composite design were used to optimize a biosynthesis medium for the production of xylanases by Streptomyces sp. P12-137 in submerged fermentation culture at pH 5.0, with wheat bran as substrate. The three variables involved in this research were the wheat bran, potassium nitrate and xylose concentrations. Statistical analysis of the results showed that, in the range studied, xylose and potassium nitrate concentrations had a significant effect on xylanase production. The optimized biosynthesis medium contained (in %, w/v): wheat bran 1.0, KNO(3) 1.0, xylose 0.5. This medium resulted in a 3-fold increased level of the xylanase (27.77 UA/ml) production compared to the initial level (8.30 UA/ml) after 120 h of fermentation, whereas the value predicted by the quadratic model was 26.45 UA/ml.
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Registered trials
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