ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2011
Faster thalamocortical processing for dark than light visual targets.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
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Who cites it
62 citing papers in PubMed.
- Optotagging in primate cortex uncovers excitatory and inhibitory neuron specializations in form vision.Nature communications · 2026Article
- A heterogeneous population code at the first synapse of vision.Nature communications · 2026Article
- Visio-spatial intelligence in athletes: comparison of field hockey players and non-athletes.Medical hypothesis, discovery & innovation ophthalmology journal · 2026Article
- Article
- Fast-Spike Interneurons in Visual Cortical Layer 5: Heterogeneous Response Properties Are Related to Thalamocortical Connectivity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Regional tuning of photoreceptor adaptation in the primate retina.Nature communications · 2024Article
- Binocular receptive-field construction in the primary visual cortex.Current biology : CB · 2024Article
- Visual Corticotectal Neurons in Awake Rabbits: Receptive Fields and Driving Monosynaptic Thalamocortical Inputs.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Contrast Sensitivity of ON and OFF Human Retinal Pathways in Myopia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Understanding contrast perception in amblyopia: a psychophysical analysis of the ON and OFF visual pathways.Frontiers in psychology · 2024Article
- Dynamic Recruitment of the Feedforward and Recurrent Mechanism for Black-White Asymmetry in the Primary Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Differences in visual stimulation between reading and walking and implications for myopia development.Journal of vision · 2023Article
- Model-Based Approach Shows ON Pathway Afferents Elicit a Transient Decrease of V1 Responses.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Luminance Contrast Shifts Dominance Balance between ON and OFF Pathways in Human Vision.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Faster Detection of "Darks" than "Brights" by Monkey Superior Colliculus Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Brain-wide ongoing activity is responsible for significant cross-trial BOLD variability.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Preferential Loss of Contrast Decrement Responses in Human Glaucoma.Investigative ophthalmology & visual science · 2022Article
- Cortical mechanisms of visual brightness.Cell reports · 2022Article
- A Computational Model of Direction Selectivity in Macaque V1 Cortex Based on Dynamic Differences between On and Off Pathways.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Article
2 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors.
Funding
Abstract
ON and OFF visual pathways originate in the retina at the synapse between photoreceptor and bipolar cells. OFF bipolar cells are shorter in length and use receptors with faster kinetics than ON bipolar cells and, therefore, process information faster. Here, we demonstrate that this temporal advantage is maintained through thalamocortical processing, with OFF visual responses reaching cortex ~3-6 ms before ON visual responses. Faster OFF visual responses could be demonstrated in recordings from large populations of cat thalamic neurons representing the center of vision (both X and Y) and from subpopulations making connection with the same cortical orientation column. While the OFF temporal advantage diminished as visual responses reached their peak, the integral of the impulse response was greater in OFF than ON neurons. Given the stimulus preferences from OFF and ON channels, our results indicate that darks are processed faster than lights in the thalamocortical pathway.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.