Evidence map›Paper›PMID 22129898›Full record

ArticleMedical science monitor : international medical journal of experimental and clinical research2011

The impact of statin therapy on long-term cardiovascular outcomes in an outpatient cardiology practice.

Hoang M Lai, Wilbert S Aronow, Anthony D Mercando, Phoenix Kalen, Harit D Desai, Kaushang Gandhi, Mala Sharma, Harshad Amin, Trung M Lai

Open access · hybridAbstract read
In one paragraph

Article in Medical science monitor : international medical journal of experimental and clinical research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Association between low-dose folic acid supplementation and blood lipids concentrations in male and female subjects with atherosclerosis risk factors.Medical science monitor : international medical journal of experimental and clinical research · 2013
    Trial
  2. Article
  3. Article
  4. The role of monocyte phenotype switching in peri-procedural myocardial injury and its involvement in statin therapy.Medical science monitor : international medical journal of experimental and clinical research · 2013
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Hoang M LaiDepartment of Medicine, New York Medical College, Valhalla, NY, USA.
Wilbert S Aronow
Anthony D Mercando
Phoenix Kalen
Harit D Desai
Kaushang Gandhi
Mala Sharma
Harshad Amin
Trung M Lai
New York Medical College · USWestchester Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStatins reduce coronary events in patients with coronary artery disease. MATERIAL/

methodsChart reviews were performed in 305 patients (217 men and 88 women, mean age 74 years) not treated with statins during the first year of being seen in an outpatient cardiology practice but subsequently treated with statins. Based on the starting date of statins use, the long-term outcomes of myocardial infarction (MI), percutaneous coronary intervention (PCI), and coronary artery bypass graft surgery (CABGS) before and after statin use were compared.

resultsMean follow-up was 65 months before statins use and 66 months after statins use. MI occurred in 31 of 305 patients (10%) before statins, and in 13 of 305 patients (4%) after statins (p < 0.01). PCI had been performed in 66 of 305 patients (22%) before statins and was performed in 41 of 305 patients (13%) after statins (p < 0.01). CABGS had been performed in 56 of 305 patients (18%) before statins and was performed in 20 of 305 patients (7%) after statins (p < 0.001). Stepwise logistic regression showed statins use was an independent risk factor for MI (odds ratio = 0.0207, 95% CI, 0.0082-0.0522, p < 0.0001), PCI (odds ratio = 0.0109, 95% CI, 0.0038-0.0315, p < 0.0001), and CABGS (odds ratio = 0.0177, 95% CI = 0.0072-0.0431, p<0.0001.)

conclusionsStatins use in an outpatient cardiology practice reduces the incidence of MI, PCI, and CABGS.

Indexed as

CardiologyOutpatientsPractice Patterns, Physicians'AgedCardiovascular DiseasesFemaleHumansHydroxymethylglutaryl-CoA Reductase InhibitorsIncidenceMaleMyocardial InfarctionMyocardial RevascularizationTime FactorsTreatment OutcomeHydroxymethylglutaryl-CoA Reductase Inhibitors

Identifiers

PMID22129898
PMCPMC3628130
OpenAlexW1995997111

What OpenQuestion holds

Texttitle and abstract
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.