Trial reportCirculation. Cardiovascular imaging2012
Provider-directed imaging stress testing reduces health care expenditures in lower-risk chest pain patients presenting to the emergency department.
Trial report in Circulation. Cardiovascular imaging, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy Evaluation of Observation Unit Cardiac Magnetic Resonance Imaging (MRI) in Patients With Intermediate Risk Acute Chest Pain
Efficacy Evaluation of the HEART Pathway in Emergency Department Patients With Acute Chest Pain
Cardiac Magnetic Resonance Imaging Strategy for the Management of Patients With Acute Chest Pain and Detectable to Elevated Troponin
Are Serial Electrocardiograms Additive to SeriAl Second-generations Troponins in Predicting Acute CoronAry Syndromes in PatienTs With Undifferentiated cHest Pain (ASAP CATH) Study
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Outcomes of emergency department observation units for geriatric assessment: a systematic review and meta-analysis.Singapore medical journal · 2026Pooled it
- Hospitalisation in short-stay units for adults with internal medicine diseases and conditions.The Cochrane database of systematic reviews · 2018Pooled it
- Cardiac Magnetic Resonance Imaging Versus Invasive-Based Strategies in Patients With Chest Pain and Detectable to Mildly Elevated Serum Troponin: A Randomized Clinical Trial.Circulation. Cardiovascular imaging · 2023Trial
- ACES (Accelerated Chest Pain Evaluation With Stress Imaging) Protocols Eliminate Testing Disparities in Patients With Chest Pain.Critical pathways in cardiology · 2019Trial
- The HEART Pathway Randomized Controlled Trial One-year Outcomes.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2019Trial
- Stress CMR reduces revascularization, hospital readmission, and recurrent cardiac testing in intermediate-risk patients with acute chest pain.JACC. Cardiovascular imaging · 2013Trial
- Appropriateness of Cardiovascular Imaging in the Initial Assessment of Possible Acute Coronary Syndrome in the Emergency Department.Reviews in cardiovascular medicine · 2022Review
- Monocyte Chemoattractant Protein-1 as a Predictor of Coronary Atherosclerosis in Patients Receiving Coronary Angiography.Critical pathways in cardiology · 2018Article
- Cost analysis of the History, ECG, Age, Risk factors, and initial Troponin (HEART) Pathway randomized control trial.The American journal of emergency medicine · 2017Article
- Myocardial deformation by strain echocardiography identifies patients with acute coronary syndrome and non-diagnostic ECG presenting in a chest pain unit: a prospective study of diagnostic accuracy.Clinical research in cardiology : official journal of the German Cardiac Society · 2016Article
- Imaging techniques for the assessment of suspected acute coronary syndromes in the emergency department.Current problems in cardiology · 2014Review
- Reduction in observation unit length of stay with coronary computed tomography angiography depends on time of emergency department presentation.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2013Article
- Emergency department observation units and the older patient.Clinics in geriatric medicine · 2013Review
- Non-ST-segment elevation acute coronary syndromes: targeted imaging to refine upstream risk stratification.Circulation. Cardiovascular imaging · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
backgroundAmong intermediate- to high-risk patients with chest pain, we have shown that a cardiac magnetic resonance (CMR) stress test strategy implemented in an observation unit (OU) reduces 1-year health care costs compared with inpatient care. In this study, we compare 2 OU strategies to determine among lower-risk patients if a mandatory CMR stress test strategy was more effective than a physicians' ability to select a stress test modality. METHODS AND
resultsOn emergency department arrival and referral to the OU for management of low- to intermediate-risk chest pain, 120 individuals were randomly assigned to receive (1) a CMR stress imaging test (n=60) or (2) a provider-selected stress test (n=60: stress echo [62%], CMR [32%], cardiac catheterization [3%], nuclear [2%], and coronary CT [2%]). No differences were detected in length of stay (median CMR=24.2 hours versus 23.8 hours, P=0.75), catheterization without revascularization (CMR=0% versus 3%), appropriateness of admission decisions (CMR 87% versus 93%, P=0.36), or 30-day acute coronary syndrome (both 3%). Median cost was higher among those randomly assigned to the CMR-mandated group ($2005 versus $1686, P<0.001).
conclusionsIn patients with lower-risk chest pain receiving emergency department-directed OU care, the ability of a physician to select a cardiac stress imaging modality (including echocardiography, CMR, or radionuclide testing) was more cost-effective than a pathway that mandates a CMR stress test. Contrary to prior observations in individuals with intermediate- to high-risk chest pain, in those with lower-risk chest pain, these results highlight the importance of physician-related choices during acute coronary syndrome diagnostic protocols. CLINICAL
trial registrationURL: http://www.clinicaltrials.gov. Unique identifier: NCT00869245.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.