ArticleThe Annals of occupational hygiene2012
Reaerosolization of MS2 bacteriophage from an N95 filtering facepiece respirator by simulated coughing.
Article in The Annals of occupational hygiene, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Exploring options for reprocessing of N95 Filtering Facepiece Respirators (N95-FFRs) amidst COVID-19 pandemic: A systematic review.PloS one · 2020Pooled it
- Quantification and characterization of manufactured nanomaterials shed from face masks.Scientific reports · 2026Article
- Effect of Face Masking on Transmission of SARS-CoV-2.Advances in experimental medicine and biology · 2024Article
- The time has come to protect healthcare workers and patients from aerosol transmissible disease.Frontiers in public health · 2024Article
- What We Are Learning from COVID-19 for Respiratory Protection: Contemporary and Emerging Issues.Polymers · 2021Review
- Modeling the efficiency of UV at 254 nm for disinfecting the different layers within N95 respirators.Journal of biophotonics · 2021Article
- Principles and practice for SARS-CoV-2 decontamination of N95 masks with UV-C.Biophysical journal · 2021Review
- Analysis of Taiwan's Mask Collection and Plan Evasion during the COVID-19 Pandemic.International journal of environmental research and public health · 2021Article
- Viruses such as SARS-CoV-2 can be partially shielded from UV radiation when in particles generated by sneezing or coughing: Numerical simulations.Journal of quantitative spectroscopy & radiative transfer · 2021Article
- Evaluation of 2 Ultraviolet-C Light Boxes for Decontamination of N95 Respirators.Pathogens & immunity · 2021Article
- Reusing and/or reprocessing the N95 face respirator mask or equivalent: An integrative review.Revista latino-americana de enfermagem · 2021Review
- Mask shortage during epidemics and pandemics: a scoping review of interventions to overcome limited supply.BMJ open · 2020Article
- Strategies for Optimizing the Supply of N95 Filtering Facepiece Respirators During the Coronavirus Disease 2019 (COVID-19) Pandemic.Disaster medicine and public health preparedness · 2020Article
- The COVID-19 pandemic, personal protective equipment and respirator: A narrative review.International journal of clinical practice · 2020Review
- Options for Personal Protective Equipment During the SARS-CoV-2 Pandemic Used in New Orleans, Louisiana.The journal of allergy and clinical immunology. In practice · 2020Article
- Evidence for decontamination of single-use filtering facepiece respirators.The Journal of hospital infection · 2020Review
- A Review of Decontamination Methods for Filtering Facepiece Respirators.Journal of the International Society for Respiratory Protection · 2020Article
- A comparison of facemask and respirator filtration test methods.Journal of occupational and environmental hygiene · 2017Article
- Cellulose-based virus-retentive filters: a review.Re/views in environmental science and bio/technology · 2017Review
- Validation and application of models to predict facemask influenza contamination in healthcare settings.Risk analysis : an official publication of the Society for Risk Analysis · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The supply of N95 filtering facepiece respirators (FFRs) may not be adequate to match demand during a pandemic outbreak. One possible strategy to maintain supplies in healthcare settings is to extend FFR use for multiple patient encounters; however, contaminated FFRs may serve as a source for the airborne transmission of virus particles. In this study, reaerosolization of virus particles from contaminated FFRs was examined using bacteriophage MS2 as a surrogate for airborne pathogenic viruses. MS2 was applied to FFRs as droplets or droplet nuclei. A simulated cough (370 l min(-1) peak flow) provided reverse airflow through the contaminated FFR. The number and size of the reaerosolized particles were measured using gelatin filters and an Andersen Cascade Impactor (ACI). Two droplet nuclei challenges produced higher percentages of reaerosolized particles (0.21 and 0.08%) than a droplet challenge (<0.0001%). Overall, the ACI-determined size distribution of the reaerosolized particles was larger than the characterized loading virus aerosol. This study demonstrates that only a small percentage of viable MS2 viruses was reaerosolized from FFRs by reverse airflow under the conditions evaluated, suggesting that the risks of exposure due to reaerosolization associated with extended use can be considered negligible for most respiratory viruses. However, risk assessments should be updated as new viruses emerge and better workplace exposure data becomes available.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.