ArticleBiological trace element research2012
Nanoparticles of selenium as species with stronger physiological effects in sheep in comparison with sodium selenite.
Article in Biological trace element research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 103 citations in OpenAlex.
- Development and biomarker-based validation of a novel feed formulation for managing production diseases in dairy buffaloes.Frontiers in veterinary science · 2026Article
- Potential Relationship Between Decreased Serum Selenium Levels and Oxidative Stress in Periodontitis Stage III-IV.Biological trace element research · 2025Article
- Selenium-Enriched Aspergillus oryzae A02 Enhances Testicular Antioxidant Capacity in Mice by Regulating Intestinal Microbiota and Serum Metabolite.Biological trace element research · 2025Article
- Comparative Study of Red and Grey Selenium Nanoparticles on Organ-Specific Selenium Deposition and Growth Performance in Japanese Quails.Nanomaterials (Basel, Switzerland) · 2025Article
- Antioxidant and Anticancer Activities of Bio-Synthesized Selenium Nanoparticles by Escherichia coli.Asian Pacific journal of cancer prevention : APJCP · 2025Article
- Exploring the potential of selenium nanoparticles and fabricated selenium nanoparticles @vitamin C nanocomposite in mitigating nicotine-induced testicular toxicity in rats.Toxicology research · 2024Article
- Theranostic applications of selenium nanomedicines against lung cancer.Journal of nanobiotechnology · 2023Review
- Biogenic Selenium Nanoparticles in Biomedical Sciences: Properties, Current Trends, Novel Opportunities and Emerging Challenges in Theranostic Nanomedicine.Nanomaterials (Basel, Switzerland) · 2023Review
- Antifungal Activity of Selenium Nanoparticles Obtained by Plant-Mediated Synthesis.Antibiotics (Basel, Switzerland) · 2023Article
- Article
- The effect of metal-containing nanoparticles on the health, performance and production of livestock animals and poultry.The veterinary quarterly · 2022Review
- Effect of Phytosynthesized Selenium and Cerium Oxide Nanoparticles on Wheat (Molecules (Basel, Switzerland) · 2022Article
- Modulation of the Functional State of Mouse Neutrophils by Selenium Nanoparticles In Vivo.International journal of molecular sciences · 2022Article
- Effects of Supranutritional Selenium Nanoparticles on Immune and Antioxidant Capacity in Sprague-Dawley Rats.Biological trace element research · 2021Article
- Selenium Nanoparticles as Candidates for Antibacterial Substitutes and Supplements against Multidrug-Resistant Bacteria.Biomolecules · 2021Article
- Nanominerals: Fabrication Methods, Benefits and Hazards, and Their Applications in Ruminants with Special Reference to Selenium and Zinc Nanoparticles.Animals : an open access journal from MDPI · 2021Review
- Antagonistic effect of different selenium type on green synthesized silver nanoparticle toxicity on Oreochromis niloticus: oxidative stress biomarkers.Environmental science and pollution research international · 2021Article
- Dietary supranutritional supplementation of selenium-enriched yeast improves feed efficiency and blood antioxidant status of growing lambs reared under warm environmental condition.Tropical animal health and production · 2021Article
- Stimulatory effects of nano-selenium and conjugated linoleic acid on antioxidant activity, trace minerals, and gene expression response of growing male Moghani lambs.Veterinary research forum : an international quarterly journal · 2020Article
- Biogenic selenium nanoparticles synthesized byInternational journal of nanomedicine · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study was designed to compare the effects of nano red selenium and sodium selenite on the antioxidative activities of neutrophils and the hematological parameters in sheep. Fifteen sheep were randomly allocated into three groups. Groups 1 and 2 received selenium nanoparticles orally at 1 mg/kg and sodium selenite at 1 mg Se/kg for 10 consecutive days; group 3 served as the control. To assess the degrees of oxidative stress and of lipid peroxidation of the cellular membranes, the levels of thiobarbituric acid reactive substances (TBARS) were determined in serum samples that were collected at different supplementation intervals, i.e., after 0, 10, 20, and 30 days. In addition, hematological parameters in the serum samples were measured by routine procedures. It was found that TBARS levels in groups 1 and 2 were significantly higher on days 20 and 30 compared to the basal level on day 0. It was also found that on day 30, the TBARS activities in both treated groups were significantly higher than those of the controls (P < 0.05). These findings may explain the seemingly paradoxical effects of supplemental selenium on the indicators of oxidative stress, as the levels of TBARS were generally expected to decrease in the presence of selenium. There were no significant differences between the PCV and RBC values in the three groups. The white blood cell count (WBC) in group 1 showed a significant increase on days 20 and 30 in comparison with the control group. However, in group 2, there was a significant increase of the WBC value just on day 20 in comparison with the control group. Also, there were significant increases of the neutrophil counts and significant decreases of the lymphocyte counts on day 10 in group 1, in comparison with those in group 2 and controls, and on days 20 and 30 in groups 1 and 2 in comparison with those in the control group.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.