Evidence map›Paper›PMID 22127357›Full record

ArticleStrahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]2011

Effect of photon-beam energy on VMAT and IMRT treatment plan quality and dosimetric accuracy for advanced prostate cancer.

Marlies Pasler, Dietmar Georg, Holger Wirtz, Johannes Lutterbach

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Quasi-VMAT in high-grade glioma radiation therapy.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2013
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marlies PaslerLake Constance Radiation Oncology Center Singen-Friedrichshafen, Singen, Germany.
Dietmar Georg
Holger Wirtz
Johannes Lutterbach

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe goal of the research was to evaluate treatment plan quality and dosimetric accuracy of volumetric modulated arc therapy (VMAT) and intensity-modulated radiotherapy (IMRT) plans using 6, 10, and 15 MV photon beams for prostate cancer including lymph nodes.

methodsIn this retrospective study, VMAT and IMRT plans were generated with the Pinnacle© treatment planning system (TPS) (V9.0) for 10 prostate cancer cases. Each plan consisted of two target volumes: PTV(B) included the prostate bed, PTV(PC+LN) contained PTV(B) and lymph nodes. For plan evaluation statistics, the homogeneity index, conformity index, mean doses, and near-max doses to organs at risk (OAR) were analyzed. Treatment time and number of monitor units were assessed to compare delivery efficiency. Dosimetric plan verification was performed with a 2D ionization chamber array placed in a full scatter phantom.

resultsNo differences were found for target and OAR parameters in low and high energy photon beam plans for both VMAT and IMRT. A slightly higher low dose volume was detected for 6 MV VMAT plans (normal tissue: D(mean) = 16.47 Gy) compared to 10 and 15 MV VMAT plans (D(mean) = 15.90 Gy and 15.74 Gy, respectively), similar to the findings in IMRT. In VMAT, > 96% of detector points passed the 3%/ 3 mm γ criterion; marginally better accuracy was found in IMRT (> 97%).

conclusionFor static and rotational IMRT, 15 MV photons did not show advantages over 6 and 10 MV high energy photon beams in large volume pelvic plans. For the investigated TPS and linac combination, 10 MV photon beams can be used as the general purpose energy for intensity modulation.

Indexed as

Quality Assurance, Health CareHumansMaleNeoplasm StagingOrgans at RiskPhotonsProstatic NeoplasmsRadiometryRadiotherapy DosageRadiotherapy, High-EnergyRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-Assisted

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.