ArticleNutrition research and practice2011
Effects of freeze-dried cranberry powder on serum lipids and inflammatory markers in lipopolysaccharide treated rats fed an atherogenic diet.
Article in Nutrition research and practice, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Cranberry fruit powder (Flowens™) improves lower urinary tract symptoms in men: a double-blind, randomized, placebo-controlled study.World journal of urology · 2016Trial
- The Effect of Cranberry Consumption on C-Reactive Protein and Interleukin-6: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Food science & nutrition · 2026Review
- Cranberry extract attenuates indomethacin-induced gastriculcer in rats via its potential atioxidant and anti-inflammatory effects.Journal of molecular histology · 2025Article
- Natural product-based treatment potential for type 2 diabetes mellitus and cardiovascular disease.World journal of diabetes · 2024Article
- Beneficial effects of cranberry juice enriched with omega-3 fatty acids in patients with type 2 diabetic and periodontal disease: A randomized pilot clinical trial.Journal of advanced periodontology & implant dentistry · 2024Article
- A comprehensive review of summer savory (Frontiers in pharmacology · 2023Review
- Highly Active Cranberry's Polyphenolic Fraction: New Advances in Processing and Clinical Applications.Nutrients · 2021Review
- Co-supplementation of isomalto-oligosaccharides potentiates metabolic health benefits of polyphenol-rich cranberry extract in high fat diet-fed mice via enhanced gut butyrate production.European journal of nutrition · 2018Article
- Dietary feeding of freeze-dried whole cranberry inhibits intestinal tumor development inOncotarget · 2017Article
- Effects of cranberry extracts on gene expression in THP-1 cells.Food science & nutrition · 2017Article
- Impact of Cranberries on Gut Microbiota and Cardiometabolic Health: Proceedings of the Cranberry Health Research Conference 2015.Advances in nutrition (Bethesda, Md.) · 2016Review
- Constituents of French Marigold (Tagetes patula L.) Flowers Protect Jurkat T-Cells against Oxidative Stress.Oxidative medicine and cellular longevity · 2016Article
- Novel quercetin-3-O-glucoside eicosapentaenoic acid ester ameliorates inflammation and hyperlipidemia.Inflammopharmacology · 2015Article
- Effects of cranberry powder on biomarkers of oxidative stress and glucose control in db/db mice.Nutrition research and practice · 2013Article
- Cranberries and their bioactive constituents in human health.Advances in nutrition (Bethesda, Md.) · 2013Review
- Rosmarinic acid-rich extracts of summer savory (Satureja hortensis L.) protect Jurkat T cells against oxidative stress.Oxidative medicine and cellular longevity · 2013Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study investigated the effects of freeze-dried cranberry powder on anti-inflammation and lipid profiles of lipopolysaccharide (LPS)-treated rats fed an atherogenic diet for 6 weeks. Forty Sprague-Dawley male rats (6-weeks-old) were equally divided into the following five groups: 1) normal diet group + saline (NC); 2) atherogenic diet + saline (HFC); 3) atherogenic diet + LPS (HL); 4) atherogenic diet with 5% cranberry power + LPS (C5); 5) atherogenic diet with 10% cranberry power + LPS (C10). LPS (0.5 mg/kg) was injected into the abdominal cavities of rats 18 hours prior to sacrifice. At the end of the experimental period, we measured serum lipid profiles as well as levels of serum C-reactive protein (CRP), nitric oxide (NO), and pro-inflammatory cytokines such as tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, IL-6, and IL-10 as an anti-inflammatory cytokine. The mean serum high density lipoprotein (HDL)-cholesterol level in C5 rats was significantly higher than that in NC and HL rats (P < 0.05). The mean serum levels of CRP and IL-1β were significantly lower (P < 0.05) in the cranberry powder groups compared to those in HL rats. Additionally, mean serum IL-6 levels tended to be lower in the cranberry groups than that in the HL group, whereas serum IL-10 and NO showed 29% and 88% higher mean values in the C5 group and 49% and 24% higher in the C10 group than those in the HL group, respectively. These results suggest that freeze-dried cranberry powder may have beneficial effects on cardiovascular diseases by modifying serum lipids and the early inflammatory response.
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