Evidence map›Paper›PMID 22125280›Full record

ArticleInvestigative ophthalmology & visual science2012

The accommodative lag of the young hyperopic patient.

T Rowan Candy, Kathryn H Gray, Christy C Hohenbary, Don W Lyon

Open access · bronzeAbstract read
In one paragraph

Article in Investigative ophthalmology & visual science, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Review
  3. Impact of uncorrected hyperopia on visual function and academic performance in preschool and school-age children.Optometry and vision science : official publication of the American Academy of Optometry · 2026
    Review
  4. Attention to text and pictures during storybook reading in preschool children with moderate hyperopia.Optometry and vision science : official publication of the American Academy of Optometry · 2026
    Article
  5. Article
  6. The QuickSee autorefractor reliably measures the accommodative response in children compared with the Shin-Nippon autorefractor.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025
    Article
  7. Article
  8. How Do Most Young Moderate Hyperopes Avoid Strabismus?Investigative ophthalmology & visual science · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Journal of ophthalmology · 2019
    Article
  15. Impact of Cognitive Demand during Sustained Near Tasks in Children and Adults.Optometry and vision science : official publication of the American Academy of Optometry · 2018
    Article
  16. Blur Detection, Depth of Field, and Accommodation in Emmetropic and Hyperopic Children.Optometry and vision science : official publication of the American Academy of Optometry · 2018
    Article
  17. Attention and Visual Motor Integration in Young Children with Uncorrected Hyperopia.Optometry and vision science : official publication of the American Academy of Optometry · 2017
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

T Rowan CandyIndiana University School of Optometry, Bloomington, Indiana 47405, USA. rcandy@indiana.edu
Kathryn H Gray
Christy C Hohenbary
Don W Lyon
Indiana University Bloomington · US

Funding

Accommodation and Defocus in the Infant Visual SystemR01EY014460 · NEI · TRUSTEES OF INDIANA UNIVERSITY · PI CANDY, T ROWAN · 2003 to 2025
$7.5M
NEI NIH HHS R01 EY014460
6 · The paper itself

Abstract

purposeTo determine the accommodative accuracy of infants and young children before they had had any form of clinical intervention or treatment, in an attempt to determine the difference between 'normal' and 'abnormal' visual experience for these individuals.

methodsNott retinoscopy was performed on 111 subjects in binocular viewing conditions at a viewing distance of 50 cm. The target was a naturalistic cartoon image with a broadband spatial frequency amplitude spectrum.

resultsAccommodative accuracy was not related to age (4-90 months). In the group found to have no apparent clinical abnormality (n = 71), the mean lag in the more hyperopic meridian of the least ametropic eye was 0.34 diopters (D). When considering the group as a whole, those with less than approximately 4 D of hyperopia demonstrated similar lags, while those with higher hyperopia, amblyopia, or strabismus had more variable lags. An ROC analysis designed to detect hyperopia >5 D in any meridian, amblyopia and/or strabismus had an area under the curve of 0.90 (95% confidence interval [CI], 0.82 to 0.95), and for a lag criterion of 1.3 D had a sensitivity of 83.3% and a specificity of 96.5%.

conclusionsThese data from a relatively small but broad sampling of age and clinical status suggest that clinically normal young infants and children with low amounts of hyperopia have similar lags of accommodation from the first few months after birth. Subjects with greater than 4 D of hyperopia, or amblyopia or strabismus, have more variable lags and therefore evidence of abnormal visual experience.

Indexed as

Accommodation, OcularAmblyopiaChildChild, PreschoolCross-Sectional StudiesFemaleHumansHyperopiaInfantMaleRetinoscopyStrabismusVision, Binocular

Identifiers

PMID22125280
PMCPMC3292355
OpenAlexW1999326055

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.