Evidence map›Paper›PMID 22124446›Full record

ArticleInternational journal of obesity (2005)2012

Contribution of visceral fat accumulation to carotid intima-media thickness in a Chinese population.

Y Wang, X Ma, M Zhou, W Zong, L Zhang, Y Hao, J Zhu, Y Xiao, D Li, Y Bao and 1 more

Open access · hybridAbstract read
In one paragraph

Article in International journal of obesity (2005), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 43 citations in OpenAlex.

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  7. A metagenome-wide association study of gut microbiome and visceral fat accumulation.Computational and structural biotechnology journal · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Y WangDepartment of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, China.
X Ma
M Zhou
W Zong
L Zhang
Y Hao
J Zhu
Y Xiao
D Li
Y Bao
W Jia
Shanghai Jiao Tong University · CNShanghai Sixth People's Hospital · CNShanghai Clinical Research Center · CNAmerican Institute of Ultrasound in Medicine · USDiabetes Foundation · INShanghai Municipal Center For Disease Control Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveRecent observational studies have reported that body fat distribution might be differentially associated with subclinical atherosclerosis. We previously reported that visceral fat area (VFA) ≥ 80 cm2 is the optimal cutoff for identifying abdominal obesity in Chinese subjects. We examined whether VFA ≥ 80 cm2 reflects the association between abdominal obesity and subclinical atherosclerosis, and if determination of the visceral fat quantity is useful for assessing subclinical atherosclerosis in asymptomatic individuals. METHODS AND

resultsParticipants (N=1005, men 515, women 490, 34-66 years) free of cardiovascular disease underwent magnetic resonance imaging and carotid ultrasound assessment to quantify VFA and carotid intima-media thickness (C-IMT). Overweight/obese subjects (body mass index (BMI) ≥ 25.0 kg m(-2)) had a higher C-IMT than lean subjects (BMI <25.0 kg m(-2)) (P<0.01). Subjects with VFA ≥ 80 cm2 had significantly higher C-IMT than those without abdominal obesity regardless of BMI (P<0.01). By multivariate regression analysis adjusted for anthropometric measurements and cardiovascular risk factors, waist circumference but not BMI was independently correlated with C-IMT in men (P<0.001). Similar findings were observed with an accurate obesity indices adjusted model, which showed that VFA was an independent risk factor for increased C-IMT in men but not in women.

conclusionsVFA 80 cm2 effectively identified carotid atherosclerosis for both lean and obese individuals in middle-aged Chinese men.

Indexed as

Adipose TissueAdultAgedAsian PeopleBody CompositionBody Fat DistributionBody Mass IndexCarotid Artery DiseasesCarotid Intima-Media ThicknessChinaFemaleHumansIntra-Abdominal FatMaleMiddle AgedObesity

Identifiers

PMID22124446
PMCPMC3448043
OpenAlexW1979296577

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.