Trial reportArchives of internal medicine2011
Improving care after myocardial infarction using a 2-year internet-delivered intervention: the Department of Veterans Affairs myocardial infarction-plus cluster-randomized trial.
Trial report in Archives of internal medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00126750 (MI-Plus), which is not on this map. Cited by 18 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
MI-Plus: Web-enhanced Guideline Implementation for Post MI CBOC Patients
Who cites it
18 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- Methods to derive composite indicators used for quality and safety measurement and monitoring in healthcare: a scoping review.Frontiers in health services · 2026Pooled it
- Efficacy of sustained knowledge translation (KT) interventions in chronic disease management in older adults: systematic review and meta-analysis of complex interventions.BMC medicine · 2023Pooled it
- Reporting non-adherence in cluster randomised trials: A systematic review.Clinical trials (London, England) · 2018Pooled it
- E-learning for health professionals.The Cochrane database of systematic reviews · 2018Pooled it
- Pooled it
- Patient education in the management of coronary heart disease.The Cochrane database of systematic reviews · 2017Pooled it
- Internet-based interventions for the secondary prevention of coronary heart disease.The Cochrane database of systematic reviews · 2015Pooled it
- Interventions to improve adherence to cardiovascular disease guidelines: a systematic review.BMC family practice · 2015Pooled it
- Pooled it
- Public trust in genomic risk assessment for type 2 diabetes mellitus.Journal of genetic counseling · 2014Trial
- Impact of Continuous Nursing Intervention Delivered via Internet+ Platform on Inflammatory Responses in Ulcerative Colitis Patients.Patient preference and adherence · 2026Article
- Implementing adaptive e-learning for newborn care in Tanzania: an observational study of provider engagement and knowledge gains.BMJ open · 2024Observational
- Evaluating the Effectiveness of the Computer-Based Education Platform, Pharmacy5in5, on Pharmacists' Knowledge of Anticholinergic Toxicity Using a Randomized Controlled Trial.Pharmacy (Basel, Switzerland) · 2022Article
- E-learning to teach medical students about acute otitis media: A randomized controlled trial.Paediatrics & child health · 2021Article
- CONSORT extension for the reporting of randomised controlled trials conducted using cohorts and routinely collected data (CONSORT-ROUTINE): checklist with explanation and elaboration.BMJ (Clinical research ed.) · 2021Article
- The Origin of Variation in Primary Care Process and Outcome Indicators: Patients, Professionals, Centers, and Health Districts.Medicine · 2015Observational
- Dissemination and implementation of comparative effectiveness evidence: key informant interviews with Clinical and Translational Science Award institutions.Journal of comparative effectiveness research · 2013Article
- Improving guidelines for the management of coronary heart disease risk factors.Archives of medical science : AMS · 2011Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundCardiovascular risk reduction in ambulatory patients who survive myocardial infarction (MI) is effective but underused. We sought to evaluate a provider-directed, Internet-delivered intervention to improve cardiovascular management for post-MI outpatients.
methodsThe Department of Veterans Affairs (VA) MI-Plus study was a cluster-randomized trial involving 168 community-based primary care clinics and 847 providers in 26 states, the Virgin Islands, and Puerto Rico, from January 1, 2002, through December 31, 2008, with the clinic as the randomization unit. We collected administrative data for 15,847 post-MI patients and medical record data for 10,452 of these. A multicomponent, Internet-delivered intervention included quarterly educational modules, practice guidelines, monthly literature summaries, and automated e-mail reminders delivered to providers for 27 months. Main outcome measures included percentage of patients who achieved each of 7 clinical indicators, a composite score of the 7 clinical indicators, and mean low-density lipoprotein cholesterol and hemoglobin A(1c) levels.
resultsClinics had a median of 3 providers (interquartile range, 2-6), with a median of 50.0% of providers (33.3%-66.7%) participating in the study. Patients in intervention clinics had greater improvements (from 70.0% to 85.5%) in the percentages prescribed β-blockers than patients in control clinics (71.9% to 84.0%; adjusted improvement gain for intervention vs control, 2.6%; 95% CI, 0.1%-4.1%). We found nonsignificant differences in improvements favoring patients in intervention clinics for 5 of 6 remaining clinical indicators and levels of low-density lipoprotein cholesterol and hemoglobin A(1c).
conclusionA longitudinal, Internet-delivered intervention improved only 1 of 7 clinical indicators of cardiovascular management in ambulatory post-MI patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.