Trial reportArchives of internal medicine2011
Chronic disease management for tobacco dependence: a randomized, controlled trial.
Trial report in Archives of internal medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00309296 (Longitudinal Care), which is not on this map. Cited by 55 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Longitudinal Care: Smoking Reduction to Aid Cessation; Part of Hatsukami's Tobacco Exposure Reduction
Who cites it
55 citing papers in PubMed, 5 syntheses or guidelines pooled it, 92 citations in OpenAlex.
- Differences in the effectiveness of individual-level smoking cessation interventions by socioeconomic status.The Cochrane database of systematic reviews · 2025Pooled it
- Relapse prevention interventions for smoking cessation.The Cochrane database of systematic reviews · 2019Pooled it
- Telephone counselling for smoking cessation.The Cochrane database of systematic reviews · 2019Pooled it
- Relapse prevention interventions for smoking cessation.The Cochrane database of systematic reviews · 2019Pooled it
- Non-adherence to telemedicine interventions for drug users: systematic review.Revista de saude publica · 2014Pooled it
- Repeat Behavioral Counseling, With and Without Combination Nicotine Replacement Therapy, for Smoking Cessation Among People With HIV in South Africa.AIDS and behavior · 2026Trial
- Long-term engagement in smoking cessation campaign: A mixed methods randomized trial.PloS one · 2025Trial
- Tobacco Quitline Retreatment Interventions Among Adults With Socioeconomic Disadvantage: A Factorial Randomized Clinical Trial.JAMA network open · 2024Trial
- What to do after smoking relapse? A sequential multiple assignment randomized trial of chronic care smoking treatments.Addiction (Abingdon, England) · 2024Trial
- A smoking cessation intervention for rural veterans tailored to individual risk factors: A multicenter randomized clinical trial.Journal of substance use and addiction treatment · 2024Trial
- Optimizing Longitudinal Tobacco Cessation Treatment in Lung Cancer Screening: A Sequential, Multiple Assignment, Randomized Trial.JAMA network open · 2023Trial
- Evaluation of a Pharmacist-Linked Smoking Cessation Intervention for Adults Experiencing Homelessness.Substance use & misuse · 2023Trial
- Chronic care treatment for smoking cessation in patients with serious mental illness: a pilot randomized trial.BMC psychiatry · 2021Trial
- Effect of Long-term Nicotine Replacement Therapy vs Standard Smoking Cessation for Smokers With Chronic Lung Disease: A Randomized Clinical Trial.JAMA network open · 2018Trial
- Program for lung cancer screening and tobacco cessation: Study protocol of a sequential, multiple assignment, randomized trial.Contemporary clinical trials · 2017Trial
- Longitudinal Care Improves Cessation in Smokers Who Do Not Initially Respond to Treatment by Increasing Cessation Self-Efficacy, Satisfaction, and Readiness to Quit: A Mediated Moderation Analysis.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2016Trial
- Comparative effectiveness of motivation phase intervention components for use with smokers unwilling to quit: a factorial screening experiment.Addiction (Abingdon, England) · 2016Trial
- Long-term nicotine replacement therapy: a randomized clinical trial.JAMA internal medicine · 2015Trial
- Retreatment with varenicline for smoking cessation in smokers who have previously taken varenicline: a randomized, placebo-controlled trial.Clinical pharmacology and therapeutics · 2014Trial
- The relation between social support and smoking cessation: revisiting an established measure to improve prediction.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2014Trial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
backgroundTobacco dependence disorder is a chronic relapsing condition, yet treatment is delivered in discrete episodes of care that yield disappointing long-term quit rates.
methodsWe conducted a randomized controlled trial from June 1, 2004, through May 31, 2009, to compare telephone-based chronic disease management (1 year; longitudinal care [LC]) with evidence-based treatment (8 weeks; usual care [UC]) for tobacco dependence. A total of 443 smokers each received 5 telephone counseling calls and nicotine replacement therapy by mail for 4 weeks. They were then randomized to UC (2 additional calls) or LC (continued counseling and nicotine replacement therapy for an additional 48 weeks). Longitudinal care targeted repeat quit attempts and interim smoking reduction for relapsers. The primary outcome was 6 months of prolonged abstinence measured at 18 months of follow-up.
resultsAt 18 months, 30.2% of LC participants reported 6 months of abstinence from smoking, compared with 23.5% in UC (unadjusted, P = .13). Multivariate analysis showed that LC (adjusted odds ratio, 1.74; 95% CI, 1.08-2.80), quit attempts in past year (1.75; 1.06-2.89), baseline cigarettes per day (0.95; 0.92-0.99), and smoking in the 14- to 21-day interval post-quit (0.23; 0.14-0.38) predicted prolonged abstinence at 18 months. The LC participants who did not quit reduced smoking more than UC participants (significant only at 12 months). The LC participants received more counseling calls than UC participants (mean, 16.5 vs 5.8 calls; P < .001), longer total duration of counseling (283 vs 117 minutes; P < .001), and more nicotine replacement therapy (4.7 vs 2.4 boxes of patches; P < .001).
conclusionA chronic disease management approach increases both short- and long-term abstinence from smoking.
trial registrationclinicaltrials.gov Identifier: NCT00309296.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.