ArticleNucleic acids research2012
Transcription co-activator SAYP mediates the action of STAT activator.
Article in Nucleic acids research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 22 citations in OpenAlex.
- Functional Role of Bap170 Domains in Enhancer-Dependent Gene Activity in Drosophila melanogaster.Doklady. Biochemistry and biophysics · 2025Article
- Effects of Overexpression of Specific Subunits SAYP, BAP170 of the Chromatin Remodeling Complex in Drosophila Melanogaster.Doklady. Biochemistry and biophysics · 2024Article
- Subunits Med12 and Med13 of Mediator Cooperate with Subunits SAYP and Bap170 of SWI/SNF in Active Transcription inInternational journal of molecular sciences · 2024Article
- PHD finger protein 10 promotes cell proliferation by regulating CD44 transcription in gastric cancer.Heliyon · 2024Article
- Article
- Subunits of the PBAP Chromatin Remodeler Are Capable of Mediating Enhancer-Driven Transcription inInternational journal of molecular sciences · 2021Article
- The Chriz Protein Promotes the Recruitment of the Z4 Protein to the STAT-Dependent Promoters.Doklady. Biochemistry and biophysics · 2020Article
- Transcriptional quiescence in primordial germ cells.Critical reviews in biochemistry and molecular biology · 2018Review
- Identification of Novel Regulators of the JAK/STAT Signaling Pathway that Control Border Cell Migration in the Drosophila Ovary.G3 (Bethesda, Md.) · 2016Article
- On the way of revealing coactivator complexes cross-talk during transcriptional activation.Cell & bioscience · 2016Review
- Mammalian cells contain two functionally distinct PBAF complexes incorporating different isoforms of PHF10 signature subunit.Cell cycle (Georgetown, Tex.) · 2014Article
- SAYP and Brahma are important for 'repressive' and 'transient' Pol II pausing.Nucleic acids research · 2012Article
- Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Jak/STAT is an important signaling pathway mediating multiple events in development. We describe participation of metazoan co-activator SAYP/PHF10 in this pathway downstream of STAT. The latter, via its activation domain, interacts with the conserved core of SAYP. STAT is associated with the SAYP-containing co-activator complex BTFly and recruits BTFly onto genes. SAYP is necessary for stimulating STAT-driven transcription of numerous genes. Mutation of SAYP leads to maldevelopments similar to those observed in STAT mutants. Thus, SAYP is a novel co-activator mediating the action of STAT.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.