Evidence map›Paper›PMID 22123272›Full record

ArticleThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2011

Impact of Medicare Part D on antidepressant treatment, medication choice, and adherence among older adults with depression.

Julie M Donohue, Yuting Zhang, Men Aiju, Subashan Perera, Judith R Lave, Joseph T Hanlon, Charles F Reynolds

Open access · greenAbstract read
In one paragraph

Article in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 4 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 4 syntheses or guidelines pooled it, 41 citations in OpenAlex.

  1. Pharmaceutical policies: effects of regulating drug insurance schemes.The Cochrane database of systematic reviews · 2022
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  6. Definition of treatment-resistant late-life depression: Conclusions from a European Task Force Delphi process.European psychiatry : the journal of the Association of European Psychiatrists · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Julie M DonohueDepartment of Health Policy and Management, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA. jdonohue@pitt.edu
Yuting Zhang
Men Aiju
Subashan Perera
Judith R Lave
Joseph T Hanlon
Charles F Reynolds
University of Pittsburgh · USGeriatric Research Education and Clinical Center · US

Funding

VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JENNIFER S BRACH · 2004 to 2026
$28.6M
University of Pittsburgh Clinical and Translational Science InstitutionKL2RR024154 · NCRR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2006 to 2011
$22.2M
University of Pittsburgh Clinical and Translational Science InstitutionKL2TR000146 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$8.7M
Research Network Development Core (pages 329-374)P30MH071944 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REYNOLDS, CHARLES F. · 2005 to 2009
$6.7M
Pitt Integrated Clinical and Geroscience Research Training ProgramT32AG021885 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Aditi U Gurkar · 2003 to 2026
$6.7M
Longitudinal Impact of CNS Polypharmacy on Geriatric SyndromesR01AG027017 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HANLON, JOSEPH T · 2006 to 2012
$801k
Impact of Medicare Part D on Racial Disparities in Diabetes Treatment and OutcomeR01HS017695 · AHRQ · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DONOHUE, JULIE MARIE · 2009 to 2011
$628k
UPITT Program for Pharmaceutical Outcomes Research in AgingK07AG033174 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HANLON, JOSEPH T · 2009 to 2013
$461k
Racial Disparities in Older Adults: Impact of Medicare Part DR01AG034056 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HANLON, JOSEPH T · 2009 to 2010
$451k
Medicare Part D Cost-Sharing and Treatment of Mental Disorders Among Disabled DuaR34MH082682 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DONOHUE, JULIE MARIE · 2009 to 2010
$379k
AHRQ HHS R01 HS017695AHRQ HHS R01HS017695NCATS NIH HHS KL2 TR000146NCRR NIH HHS KL2 RR024154NCRR NIH HHS KL2 RR-024154-04NIA NIH HHS K07 AG033174NIA NIH HHS K07AG033174NIA NIH HHS P30 AG024827NIA NIH HHS P30AG024827NIA NIH HHS R01 AG027017NIA NIH HHS R01AG027017NIA NIH HHS R01 AG034056NIA NIH HHS R01AG034056NIA NIH HHS T32 AG021885NIA NIH HHS T32AG021885NIMH NIH HHS P30 MH071944NIMH NIH HHS P30MH71944NIMH NIH HHS R34 MH082682
6 · The paper itself

Abstract

objectivesDepression in older adults is often undertreated due, in part, to medication costs. We examined the impact of improved prescription drug coverage under Medicare Part D on use of antidepressants, medication choice, and adherence. DESIGN, SETTING AND

participantsObservational claims-based study of older adults with depression (ICD-9: 296.2, 296.3, 311, 300.4) continuously enrolled in a Medicare managed care plan between 2004 and 2007. Three groups with limited ($150 or $350 quarterly caps) or no drug coverage in 2004-2005 obtained Part D benefits in 2006. A comparison group had stable employer-sponsored coverage throughout. MEASUREMENTS: Any antidepressant prescription fill, antidepressant choice (tricyclics or monoamine oxidase inhibitors versus newer antidepressants), and adherence (80% of days covered) in the first 6 months of treatment.

results: Part D was associated with increased odds of any antidepressant use among those who previously lacked coverage (odds ratio [OR] 1.61, 95% confidence interval [CI] 1.41-1.85) but odds of use did not change among those with limited prior coverage. Use of older antidepressant agents did not change with Part D. All three groups whose coverage improved with Part D had significantly higher odds of 80% of days covered with an antidepressant (OR = 1.86 [95% CI: 1.44-2.39] for no coverage, 1.74 [95% CI: 1.25%3.42] for $150 cap; and 1.19 [95% CI: 1.06-1.34] for the $350 cap groups).

conclusionsMedicare Part D was associated with improvements in antidepressant use and adherence in depressed older adults who previously had no or limited drug coverage but not with changes in use of older agents. use and adherence in depressed older adults who previously had no or limited drug coverage but not with changes in use of older agents.

Indexed as

AgedDrug MonitoringMedicare Part DAntidepressive AgentsDepressionFemaleHumansMaleMedication Therapy ManagementPractice Patterns, Physicians'United StatesAntidepressive Agents

Identifiers

PMID22123272
PMCPMC3233981
OpenAlexW2058062543

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.