ArticleJournal of bacteriology2012
Effects of cortex peptidoglycan structure and cortex hydrolysis on the kinetics of Ca(2+)-dipicolinic acid release during Bacillus subtilis spore germination.
Article in Journal of bacteriology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 45 citations in OpenAlex.
- A mathematical kinetic model of memory iniScience · 2026Article
- New insights into the structure-based mechanism ofApplied and environmental microbiology · 2026Article
- Resistance and germination of spores ofJournal of bacteriology · 2025Article
- Sporulation at reduced water activity impairs germination kinetics ofApplied and environmental microbiology · 2025Article
- Multiple roads lead to Rome: unique morphology and chemistry of endospores, exospores, myxospores, cysts and akinetes in bacteria.Microbiology (Reading, England) · 2023Article
- Effect of oxygen on the germination and culturability of Bacillus atrophaeus spores.International microbiology : the official journal of the Spanish Society for Microbiology · 2022Article
- Heat Activation and Inactivation of Bacterial Spores: Is There an Overlap?Applied and environmental microbiology · 2022Article
- Insights into the Structure and Protein Composition ofInternational journal of molecular sciences · 2022Article
- Review
- Article
- Characterization of the Dynamic Germination of Individual Clostridium difficile Spores Using Raman Spectroscopy and Differential Interference Contrast Microscopy.Journal of bacteriology · 2015Article
- Slow leakage of Ca-dipicolinic acid from individual bacillus spores during initiation of spore germination.Journal of bacteriology · 2015Article
- Analysis of metabolism in dormant spores of Bacillus species by 31P nuclear magnetic resonance analysis of low-molecular-weight compounds.Journal of bacteriology · 2015Article
- Fighting Ebola with novel spore decontamination technologies for the military.Frontiers in microbiology · 2015Article
- High-precision fitting measurements of the kinetics of size changes during germination of individual Bacillus spores.Applied and environmental microbiology · 2014Article
- Analysis of the loss in heat and acid resistance during germination of spores of Bacillus species.Journal of bacteriology · 2014Article
- L-alanine-induced germination in Bacillus licheniformis -the impact of native gerA sequences.BMC microbiology · 2014Article
- Monitoring rates and heterogeneity of high-pressure germination of bacillus spores by phase-contrast microscopy of individual spores.Applied and environmental microbiology · 2014Article
- Topology and accessibility of germination proteins in the Bacillus subtilis spore inner membrane.Journal of bacteriology · 2013Article
- Effects of the SpoVT regulatory protein on the germination and germination protein levels of spores of Bacillus subtilis.Journal of bacteriology · 2012Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The kinetic parameters of the release of Ca(2+)-dipicolinic acid (CaDPA) during germination of spore populations and multiple individual spores of Bacillus subtilis strains with major alterations in the structure of the spore peptidoglycan (PG) cortex or lacking one or both of the two redundant enzymes involved in cortex hydrolysis (cortex-lytic enzymes [CLEs]) were determined. The lack of the CLE CwlJ greatly slowed CaDPA release with a germinant receptor (GR)-dependent germinant, l-valine, or a non-GR-dependent germinant, dodecylamine. The absence of the cortex-specific PG modification muramic acid-δ-lactam also increased the time needed for full CaDPA release during germination with both types of germinants. In contrast, increased cortex PG cross-linking was associated with faster times for initiation of CaDPA release with both l-valine and dodecylamine but not with faster CaDPA release once this release had been initiated. These data suggest that the precise structure of the spore cortex plays a significant role in determining the timing and the rate of CaDPA release during B. subtilis spore germination and, further, that this effect is independent of effects of GRs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.