SynthesisBMC musculoskeletal disorders2011
European Project on OSteoArthritis (EPOSA): methodological challenges in harmonization of existing data from five European population-based cohorts on aging.
Synthesis in BMC musculoskeletal disorders, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Physical Activity Producing Low, but Not Medium or Higher, Vertical Impacts Is Inversely Related to BMI in Older Adults: Findings From a Multicohort Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2018Pooled it
- Intra-articular autologous conditioned serum and triamcinolone injections in patients with knee osteoarthritis: a controlled, randomized, double-blind study.The Journal of international medical research · 2023Trial
- Statistical methods for retrospective harmonization of longitudinal epidemiological data: a scoping review.European journal of epidemiology · 2026Article
- Article
- SPM Differences in Gait Pattern of Women After Total Hip Replacement: A Longitudinal Study.Journal of clinical medicine · 2025Article
- A genome-wide association study identifies genetic variants associated with hip pain in the UK Biobank cohort (N = 221,127).Scientific reports · 2025Article
- Comparison of Cardiovascular Health Profiles Across Population Surveys From 5 High- to Low-Income Countries.CJC open · 2024Article
- Validation of self-reported morbidities in the Korean Atomic Bomb Survivor Cohort.Epidemiology and health · 2024Article
- Decoding the exposome: data science methodologies and implications in exposome-wide association studies (ExWASs).Exposome · 2024Article
- Cardiovascular health metrics in low and middle-income countries: A scoping review.Preventive medicine · 2023Article
- Need for Improved Collection and Harmonization of Rural Maternal Healthcare Data.Clinical obstetrics and gynecology · 2022Review
- Evaluation of a collaborative ambulatory orthopedic care program for patients with hip and knee osteoarthritis: a comparative observational cohort study.BMC musculoskeletal disorders · 2022Observational
- Data sharing across osteoarthritis research groups and disciplines: Opportunities and challenges.Osteoarthritis and cartilage open · 2022Article
- A review of harmonization methods for studying dietary patterns.Smart health (Amsterdam, Netherlands) · 2022Article
- Identification of the osteoarthritis signature gene PDK1 by machine learning and its regulatory mechanisms on chondrocyte autophagy and apoptosis.Frontiers in immunology · 2022Article
- Sleep improvement after hip arthroplasty: a study on short-stem prosthesis.International orthopaedics · 2020Article
- Chondro-protective effects of polydatin in osteoarthritis through its effect on restoring dysregulated autophagy via modulating MAPK, and PI3K/Akt signaling pathways.Scientific reports · 2019Article
- A diagnosis of knee osteoarthritis does not predict physical activity 2 years later in older adults: findings from the Hertfordshire Cohort Study.Rheumatology international · 2019Article
- Development of a clinical prediction model for the onset of functional decline in people aged 65-75 years: pooled analysis of four European cohort studies.BMC geriatrics · 2019Article
- Approaches for creating comparable measures of alcohol use symptoms: Harmonization with eight studies of criminal justice populations.Drug and alcohol dependence · 2019Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
backgroundThe European Project on OSteoArthritis (EPOSA), here presented for the first time, is a collaborative study involving five European cohort studies on aging. This project focuses on the personal and societal burden and its determinants of osteoarthritis (OA). The aim of the current report is to describe the purpose of the project, the post harmonization of the cross-national data and methodological challenges related to the harmonization process
methodsThe study includes data from cohort studies in five European countries (Germany, Italy, the Netherlands, Spain and the United Kingdom) on older community-dwelling persons aged ≥ 59 years. The study design and main characteristics of the five cohort studies are described. Post harmonization algorithms are developed by finding a "common denominator" to merge the datasets and weights are calculated to adjust for differences in age and sex distribution across the datasets.
resultsA harmonized database was developed, consisting of merged data from all participating countries. In total, 10107 persons are included in the harmonized dataset with a mean age of 72.8 years (SD 6.1). The female/male ratio is 53.3/46.7%. Some variables were difficult to harmonize due to differences in wording and categories, differences in classifications and absence of data in some countries. The post harmonization algorithms are described in detail in harmonization guidelines attached to this paper.
conclusionsThere was little evidence of agreement on the use of several core data collection instruments, in particular on the measurement of OA. The heterogeneity of OA definitions hampers comparing prevalence rates of OA, but other research questions can be investigated using high quality harmonized data. By publishing the harmonization guidelines, insight is given into (the interpretation of) all post harmonized data of the EPOSA study.
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