ArticleNanomedicine (London, England)2011
Photodynamic therapy with fullerenes in vivo: reality or a dream?
Article in Nanomedicine (London, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
69 citing papers in PubMed, 246 citations in OpenAlex.
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- Surface-coated paper packaging with nanocellulose modified with quaternary ammonium organosilane and precipitated calcium carbonate for improved water repellency and antibacterial activity.Scientific reports · 2025Article
- Multifunctional Carbon-Based Nanocomposite Hydrogels for Wound Healing and Health Management.Gels (Basel, Switzerland) · 2025Review
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- Comparative Studies of the Structural and Physicochemical Properties of the First Fullerene Derivative FD-CNanomaterials (Basel, Switzerland) · 2024Article
- Fullerene Derivatives for Tumor Treatment: Mechanisms and Application.International journal of nanomedicine · 2024Review
- Development of photoactive biomaterial using modified fullerene nanoparticles.Frontiers in chemistry · 2024Article
- Comparison of Sonodynamic Treatment Set-Ups for Cancer Cells with Organic Sonosensitizers and Nanosonosensitizers.Pharmaceutics · 2023Article
- Putting a "CPharmaceuticals (Basel, Switzerland) · 2023Article
- Nanotechnology in the COVID-19 era: Carbon-based nanomaterials as a promising solution.Carbon · 2023Review
- Tuning the Molecular Structure of Corroles to Enhance the Antibacterial Photosensitizing Activity.Pharmaceutics · 2023Article
- Silent Death by Sound: CInternational journal of molecular sciences · 2023Article
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- Injectable Nano Drug Delivery Systems for the Treatment of Breast Cancer.Pharmaceutics · 2022Review
- Enhanced Uptake and Phototoxicity of CNanomaterials (Basel, Switzerland) · 2022Article
- Multifunctional Nanoplatforms as a Novel Effective Approach in Photodynamic Therapy and Chemotherapy, to Overcome Multidrug Resistance in Cancer.Pharmaceutics · 2022Review
- Combined Action of Hyper-Harmonized Hydroxylated Fullerene Water Complex and Hyperpolarized Light Leads to Melanoma Cell Reprogramming In Vitro.Nanomaterials (Basel, Switzerland) · 2022Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Photodynamic therapy (PDT) employs the combination of nontoxic photosensitizers and visible light that is absorbed by the chromophore to produce long-lived triplet states that can carry out photochemistry in the presence of oxygen to kill cells. The closed carbon-cage structure found in fullerenes can act as a photosensitizer, especially when functionalized to impart water solubility. Although there are reports of the use of fullerenes to carry out light-mediated destruction of viruses, microorganisms and cancer cells in vitro, the use of fullerenes to mediate PDT of diseases such as cancer and infections in animal models is less well developed. It has recently been shown that fullerene PDT can be used to save the life of mice with wounds infected with pathogenic Gram-negative bacteria. Fullerene PDT has also been used to treat mouse models of various cancers including disseminated metastatic cancer in the peritoneal cavity. In vivo PDT with fullerenes represents a new application in nanomedicine.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.