Evidence map›Paper›PMID 22121455›Full record

ReviewThe Pan African medical journal2011

Childhood diarrhoea: failing conventional measures, what next?

Faraj Alkizim, Duncan Matheka, Anne Muriithi

Open access · goldAbstract readReview
In one paragraph

Review in The Pan African medical journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Faraj AlkizimDepartment of Medical Physiology, University of Nairobi.
Duncan Matheka
Anne Muriithi
University of Nairobi · KE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiarrhoea is one of the leading causes of infant mortality. This article analyzes its contribution towards the realization of millennium development goal number 4 (MDG-4).

methodsA PubMed search using keywords acute infant diarrhea together with prevalence, management, or prevention 23 of the 634 generated articles were reviewed for inclusion.

resultsWHO first expressed concern about diarrhoeal mortality in 1979. Two decades later it reported diarrhoea as the second leading cause of infant mortality worldwide. The annual death toll of 1.5 million is greater than AIDS, malaria and measles combined. Short term repercussions (dehydration, electrolyte imbalance, malnutrition, shock, death) plus long-term diminished fitness index, cognitive function, and school performance have major impact on society. Ever since its 1971 success, Oral Rehydration Therapy has been the cornerstone treatment of diarrhoea. Decreased compliance has been recorded worldwide with Kenya ranking first. Intravenous therapy is useful in preventing complications while anti-diarrhoeals and anti-microbials, are indicated in severe cases. Zinc supplementation has also proven effective, and is recommended along with rehydration. Furthermore, immunization and good hygiene prevent faecal-oral transmissions.

conclusionMDG-4 aims to reduce childhood mortality by 2/3 by 2015. Studies, however, show minimal progress, and the target is likely to be missed. Efforts must therefore be made to review existing strategies and formulate newer ones. Research priorities need to move away from perceived 'killer diseases' since far more children die in a day than have ever died from avian influenza for example.

Indexed as

AntidiarrhealsAnti-Infective AgentsChildChild MortalityChild, PreschoolDiarrheaDiarrhea, InfantileGlobal HealthHumansInfantInfant MortalityPrevalenceRehydration SolutionsAntidiarrhealsAnti-Infective AgentsRehydration SolutionsDiarrhoea researchfaecal biotherapyGastroenteritisInfant mortalityMDGNonconventional treatment

Identifiers

PMID22121455
PMCPMC3201610
OpenAlexW2027920418

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.